Gemma F Ryan
Overview
Explore the profile of Gemma F Ryan including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
137
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Recent Articles
1.
Santavanond J, Chiu Y, Tixeira R, Liu Z, Yap J, Chen K, et al.
Cell Death Dis
. 2024 Feb;
15(2):123.
PMID: 38336804
Discovery of new small molecules that can activate distinct programmed cell death pathway is of significant interest as a research tool and for the development of novel therapeutics for pathological...
2.
Jayatilleke K, Duivenvoorden H, Ryan G, Parker B, Hulett M
Cancers (Basel)
. 2023 Jun;
15(11).
PMID: 37297024
Breast cancer is the second most common human malignancy and is a major global health burden. Heparanase (HPSE) has been widely implicated in enhancing the development and progression of solid...
3.
Lay F, Ryan G, Caria S, Phan T, Veneer P, White J, et al.
FASEB J
. 2019 Feb;
33(5):6470-6482.
PMID: 30794440
Defensins are an extensive family of host defense peptides found ubiquitously across plant and animal species. In addition to protecting against infection by pathogenic microorganisms, some defensins are selectively cytotoxic...
4.
Corbo R, Ryan G, Haghighatbin M, Hogan C, Wilson D, Hulett M, et al.
Inorg Chem
. 2016 Mar;
55(6):2830-9.
PMID: 26930516
In this paper we report on the use of [NO][BF4] to access tricationic tetrakis(pyridine)gold(III) from Au powder, a species inaccessible using the more traditional (tetrahydrothiophene)AuCl route. It is then demonstrated...
5.
Poon I, Baxter A, Lay F, Mills G, Adda C, Payne J, et al.
Elife
. 2014 Apr;
3:e01808.
PMID: 24692446
Cationic antimicrobial peptides (CAPs) such as defensins are ubiquitously found innate immune molecules that often exhibit broad activity against microbial pathogens and mammalian tumor cells. Many CAPs act at the...
6.
Poon I, Goodall K, Phipps S, Chow J, Pagler E, Andrews D, et al.
Eur J Immunol
. 2014 Feb;
44(4):1016-30.
PMID: 24532362
Heparanase is a β-d-endoglucuronidase that cleaves heparan sulphate, a key component of the ECM and basement membrane. The remodelling of the ECM by heparanase has been proposed to regulate both...