Gaspard Pardon
Overview
Explore the profile of Gaspard Pardon including associated specialties, affiliations and a list of published articles.
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15
Citations
190
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0
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Recent Articles
1.
Lane K, Dow L, Castillo E, Boros R, Feinstein S, Pardon G, et al.
ACS Appl Mater Interfaces
. 2024 Dec;
17(1):174-186.
PMID: 39680735
Controlling cellular shape with micropatterning extracellular matrix (ECM) proteins on hydrogels has been shown to improve the reproducibility of the cell structure, enhancing our ability to collect statistics on single-cell...
2.
Pardon G, Roest A, Chirikian O, Birnbaum F, Lewis H, Castillo E, et al.
Nat Commun
. 2024 Jun;
15(1):5427.
PMID: 38926342
Cardiomyocytes derived from human induced pluripotent stem cells (hiPSC-CMs) are powerful in vitro models to study the mechanisms underlying cardiomyopathies and cardiotoxicity. Quantification of the contractile function in single hiPSC-CMs...
3.
Birnbaum F, Eguchi A, Pardon G, Chang A, Blau H
NPJ Regen Med
. 2022 Mar;
7(1):19.
PMID: 35304486
Duchenne muscular dystrophy (DMD) is a progressive genetic myopathy that leads to heart failure from dilated cardiomyopathy by early adulthood. Recent evidence suggests that tamoxifen, a selective estrogen receptor modulator...
4.
Kim A, Castillo E, Lane K, Torres G, Chirikian O, Wilson R, et al.
Micromachines (Basel)
. 2021 Nov;
12(11).
PMID: 34832798
Human-induced pluripotent stem cell-derived cardiomyocytes are a potentially unlimited cell source and promising patient-specific in vitro model of cardiac diseases. Yet, these cells are limited by immaturity and population heterogeneity....
5.
Vander Roest A, Liu C, Morck M, Kooiker K, Jung G, Song D, et al.
Proc Natl Acad Sci U S A
. 2021 Jun;
118(24).
PMID: 34117120
Hypertrophic cardiomyopathy (HCM) is the most common inherited form of heart disease, associated with over 1,000 mutations, many in β-cardiac myosin (MYH7). Molecular studies of myosin with different HCM mutations...
6.
Chang A, Pardon G, Chang A, Wu H, Ong S, Eguchi A, et al.
Stem Cell Reports
. 2021 May;
16(9):2169-2181.
PMID: 34019816
Duchenne muscular dystrophy (DMD) is a rare X-linked recessive disease that is associated with severe progressive muscle degeneration culminating in death due to cardiorespiratory failure. We previously observed an unexpected...
7.
Extracellular matrix micropatterning technology for whole cell cryogenic electron microscopy studies
Engel L, Gaietta G, Dow L, Swift M, Pardon G, Volkmann N, et al.
J Micromech Microeng
. 2020 Sep;
29(11).
PMID: 32879557
Cryogenic electron tomography is the highest resolution tool available for structural analysis of macromolecular organization inside cells. Micropatterning of extracellular matrix (ECM) proteins is an established cell culture technique used...
8.
Mohammed D, Pardon G, Versaevel M, Bruyere C, Alaimo L, Luciano M, et al.
Cell Mol Bioeng
. 2020 Feb;
13(1):87-98.
PMID: 32030110
Introduction: The orientation of collagen fibers in native tissues plays an important role in cell signaling and mediates the progression of tumor cells in breast cancer by a contact guidance...
9.
Zandi Shafagh R, Decrop D, Ven K, Vanderbeke A, Hanusa R, Breukers J, et al.
Microsyst Nanoeng
. 2019 Jun;
5:25.
PMID: 31231538
Patterning of micro- and nanoscale topologies and surface properties of polymer devices is of particular importance for a broad range of life science applications, including cell-adhesion assays and highly sensitive...
10.
Hillmering M, Pardon G, Vastesson A, Supekar O, Carlborg C, Brandner B, et al.
Microsyst Nanoeng
. 2019 May;
2:15043.
PMID: 31057810
Thiol-enes are a group of alternating copolymers with highly ordered networks and are used in a wide range of applications. Here, "click" chemistry photostructuring in off-stoichiometric thiol-enes is shown to...