Gary W Hoyle
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Explore the profile of Gary W Hoyle including associated specialties, affiliations and a list of published articles.
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41
Citations
723
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Recent Articles
1.
Lu H, Wise S, Speer R, Croom-Perez T, Toyoda J, Meaza I, et al.
Toxicol Sci
. 2024 Jun;
201(1):1-13.
PMID: 38867691
Hexavalent chromium [Cr(VI)] is an established human lung carcinogen, but the carcinogenesis mechanism is poorly understood. Chromosome instability, a hallmark of lung cancer, is considered a major driver of Cr(VI)-induced...
2.
Wise S, Lu H, Speer R, Wise Jr J, Young J, Toyoda J, et al.
Toxicol Appl Pharmacol
. 2022 Oct;
457:116294.
PMID: 36283442
Hexavalent chromium [Cr(VI)] is a well-known and widespread environmental contaminant associated with a variety of adverse health effects, in particular lung cancer. The primary route of exposure in humans is...
3.
Hoyle G, Schlueter C, Musah S
Methods Mol Biol
. 2018 Dec;
1894:323-330.
PMID: 30547470
Nanoparticles possess a number of useful properties that make them useful for a variety of industrial and commercial applications. The small size of nanoparticles means that they are respirable and...
4.
Poole L, Beier J, Torres-Gonzales E, Schlueter C, Hudson S, Artis A, et al.
Alcohol
. 2018 Nov;
80:53-63.
PMID: 30445135
Introduction: Alcohol use disorders are major risk factors for the development of and susceptibility to acute respiratory distress syndrome. Although these risks of alcohol consumption on the lung are well...
5.
Musah S, Chen J, Schlueter C, Humphrey Jr D, Stocke K, Hoyle M, et al.
Toxicol Appl Pharmacol
. 2018 Sep;
363:11-21.
PMID: 30189237
Chlorine is a chemical threat agent that can be harmful to humans. Acute inhalation of high levels of chlorine results in the death of airway epithelial cells and can lead...
6.
Summerhill E, Hoyle G, Jordt S, Jugg B, Martin J, Matalon S, et al.
Ann Am Thorac Soc
. 2017 Apr;
14(6):1060-1072.
PMID: 28418689
This report is based on the proceedings from the Inhalational Lung Injury Workshop jointly sponsored by the American Thoracic Society (ATS) and the National Institutes of Health (NIH) Countermeasures Against...
7.
Musah S, Schlueter C, Humphrey Jr D, Powell K, Roberts A, Hoyle G
Toxicol Appl Pharmacol
. 2016 Dec;
315:1-11.
PMID: 27913141
Chlorine is a pulmonary toxicant to which humans can be exposed through accidents or intentional releases. Acute effects of chlorine inhalation in humans and animal models have been well characterized,...
8.
Jagadapillai R, Rane M, Lin X, Roberts A, Hoyle G, Cai L, et al.
Int J Mol Sci
. 2016 Nov;
17(11).
PMID: 27834824
Diabetes is strongly associated with systemic inflammation and oxidative stress, but its effect on pulmonary vascular disease and lung function has often been disregarded. Several studies identified restrictive lung disease...
9.
Conklin D, Haberzettl P, Jagatheesan G, Kong M, Hoyle G
Toxicol Appl Pharmacol
. 2016 Sep;
324:61-72.
PMID: 27592100
Acrolein is a highly toxic, volatile, unsaturated aldehyde generated during incomplete combustion as in tobacco smoke and indoor fires. Because the transient receptor potential ankyrin 1 (TRPA1) channel mediates tobacco...
10.
Hoyle G, Svendsen E
Ann N Y Acad Sci
. 2016 Jul;
1378(1):33-40.
PMID: 27385061
Chlorine gas is a toxic respiratory irritant that is considered a chemical threat agent because of the potential for release in industrial accidents or terrorist attacks. Chlorine inhalation damages the...