Gary W Black
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Explore the profile of Gary W Black including associated specialties, affiliations and a list of published articles.
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Articles
36
Citations
274
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Recent Articles
1.
Singh W, Brown N, McCue H, Marriott S, Wilson R, Perry J, et al.
Chem Sci
. 2024 Mar;
15(13):4969-4980.
PMID: 38550701
The selective α,β-desaturation of cyclic carbonyl compounds, which are found in the core of many steroid and bioactive molecules, using green chemistry is highly desirable. To achieve this task, we...
2.
Santos S, Bommareddy R, Black G, Singh W
Front Chem
. 2024 Jan;
11:1327398.
PMID: 38283898
Lignin, a complex plant cell wall component, holds promise as a renewable aromatic carbon feedstock. p-Vanillin is a key product of lignin depolymerization and a precursor of protocatechuic acid (PCA)...
3.
Gould H, Cheung W, Finnigan J, Munoz-Munoz J, Charnock S, Black G
Metabolites
. 2023 Sep;
13(9).
PMID: 37755290
is an invaluable research tool for many fields of biology, in particular for the production of recombinant enzymes. However, the activity of many such recombinant enzymes cannot be determined using...
4.
Fungal β-glucan-facilitated cross-feeding activities between Bacteroides and Bifidobacterium species
Fernandez-Julia P, Black G, Cheung W, Van Sinderen D, Munoz-Munoz J
Commun Biol
. 2023 May;
6(1):576.
PMID: 37253778
The human gut microbiota (HGM) is comprised of a very complex network of microorganisms, which interact with the host thereby impacting on host health and well-being. β-glucan has been established...
5.
Singh W, Santos S, Yadav S, Black G, Dubey K
Biochemistry
. 2023 Apr;
62(10):1577-1587.
PMID: 37092990
A recently discovered heme-dependent enzyme tyrosine hydroxylase (TyrH) offers a green approach for functionalizing the high-strength C-H and C-F bonds in aromatic compounds. However, there is ambiguity regarding the nature...
6.
Xiang H, Ferla S, Varricchio C, Brancale A, Brown N, Black G, et al.
ACS Catal
. 2023 Mar;
13(5):3370-3378.
PMID: 36910872
The oxidative aromatization of aliphatic -heterocycles is a fundamental organic transformation for the preparation of a diverse array of heteroaromatic compounds. Despite many attempts to improve the efficiency and practicality...
7.
Singh W, Santos S, James P, Black G, Huang M, Dubey K
ACS Omega
. 2022 Jun;
7(24):21109-21118.
PMID: 35755387
Cytochrome P450 is an enzyme that catalyzes the guaiacol unit of lignin during the lignin breakdown via an aryl--demethylation reaction. This reaction is intriguing and is of commercial importance for...
8.
Finnigan J, Young C, Cook D, Charnock S, Black G
Adv Protein Chem Struct Biol
. 2020 Sep;
122:289-320.
PMID: 32951814
Cytochromes P450 (P450s) are a large superfamily of heme-containing monooxygenases. P450s are found in all Kingdoms of life and exhibit incredible diversity, both at sequence level and also on a...
9.
Lauder K, Masci D, Toscani A, Al Mekdad A, Black G, Brown N, et al.
Org Biomol Chem
. 2019 Oct;
17(40):8982-8986.
PMID: 31584061
A facile microwave assisted three-component protocol allows the synthesis of chiral aryl-1,2-mercaptoamines in water in a few minutes with high yields, bypassing the use of toxic aziridine intermediates. The chiral...
10.
Ainsley J, Mulholland A, Black G, Sparagano O, Christov C, Karabencheva-Christova T
ACS Omega
. 2019 Aug;
3(5):4847-4859.
PMID: 31458701
Many natural organic compounds with pharmaceutical applications, including antibiotics (chlortetracycline and vancomycin), antifungal compounds (pyrrolnitrin), and chemotherapeutics (salinosporamide A and rebeccamycin) are chlorinated. Halogenating enzymes like tryptophan 7-halogenase (PrnA) and...