Gary T ZeRuth
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Explore the profile of Gary T ZeRuth including associated specialties, affiliations and a list of published articles.
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7
Citations
153
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Recent Articles
1.
Grieve L, Rani A, ZeRuth G
Islets
. 2024 Apr;
16(1):2344622.
PMID: 38652652
Chronically elevated levels of glucose are deleterious to pancreatic β cells and contribute to β cell dysfunction, which is characterized by decreased insulin production and a loss of β cell...
2.
Hammond-Weinberger D, ZeRuth G
J Vis Exp
. 2020 Feb;
(155).
PMID: 32065134
Immunohistochemistry is a widely used technique to explore protein expression and localization during both normal developmental and disease states. Although many immunohistochemistry protocols have been optimized for mammalian tissue and...
3.
Hoard T, Yang X, Jetten A, ZeRuth G
Heliyon
. 2018 Aug;
4(7):e00709.
PMID: 30094379
Gli-similar 3 (Glis3) is Krüppel-like transcription factor associated with the transcriptional regulation of insulin. Mutations within the Glis3 locus have been implicated in a number of pathologies including diabetes and...
4.
ZeRuth G, Williams J, Cole Y, Jetten A
PLoS One
. 2015 Jul;
10(7):e0131303.
PMID: 26147758
The transcription factor Gli-similar 3 (Glis3) plays a critical role in the generation of pancreatic ß cells and the regulation insulin gene transcription and has been implicated in the development...
5.
The Krüppel-like protein Gli-similar 3 (Glis3) functions as a key regulator of insulin transcription
ZeRuth G, Takeda Y, Jetten A
Mol Endocrinol
. 2013 Aug;
27(10):1692-705.
PMID: 23927931
Transcriptional regulation of insulin in pancreatic β-cells is mediated primarily through enhancer elements located within the 5' upstream regulatory region of the preproinsulin gene. Recently, the Krüppel-like transcription factor, Gli-similar...
6.
ZeRuth G, Yang X, Jetten A
J Biol Chem
. 2011 May;
286(25):22077-89.
PMID: 21543335
Glis3 is a member of the Glis subfamily of Krüppel-like zinc finger transcription factors. Recently, Glis3 has been linked to both type I and type II diabetes and shown to...
7.
Scott K, Sievert S, Abril F, Ball L, Barrett C, Blake R, et al.
PLoS Biol
. 2006 Nov;
4(12):e383.
PMID: 17105352
Presented here is the complete genome sequence of Thiomicrospira crunogena XCL-2, representative of ubiquitous chemolithoautotrophic sulfur-oxidizing bacteria isolated from deep-sea hydrothermal vents. This gammaproteobacterium has a single chromosome (2,427,734 base...