Gary Reynolds
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Explore the profile of Gary Reynolds including associated specialties, affiliations and a list of published articles.
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69
Citations
4126
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Recent Articles
11.
Reynolds G
Immunol Rev
. 2023 Jul;
318(1):51-60.
PMID: 37435963
Immune checkpoint inhibitors are now an established treatment in the management of a range of cancers. Their success means that their use is likely to increase in future in terms...
12.
Kumasaka N, Rostom R, Huang N, Polanski K, Meyer K, Patel S, et al.
Nat Genet
. 2023 Jun;
55(6):1066-1075.
PMID: 37308670
Common genetic variants across individuals modulate the cellular response to pathogens and are implicated in diverse immune pathologies, yet how they dynamically alter the response upon infection is not well...
13.
Pallett L, Swadling L, Diniz M, Maini A, Schwabenland M, Dalmau Gasull A, et al.
Nature
. 2023 Jan;
614(7947):334-342.
PMID: 36697826
The liver is bathed in bacterial products, including lipopolysaccharide transported from the intestinal portal vasculature, but maintains a state of tolerance that is exploited by persistent pathogens and tumours. The...
14.
Corovic A, Wall C, Nus M, Gopalan D, Huang Y, Imaz M, et al.
J Am Coll Cardiol
. 2023 Jan;
81(4):336-354.
PMID: 36697134
Background: Assessing inflammatory disease activity in large vessel vasculitis (LVV) can be challenging by conventional measures. Objectives: We aimed to investigate somatostatin receptor 2 (SST) as a novel inflammation-specific molecular...
15.
Reynolds G, Tirard A, Villani A
Immunity
. 2022 Mar;
55(3):380-382.
PMID: 35263562
The presumed common origin of plasmacytoid and conventional dendritic cells has been the contentious subject of recent debate. In this issue of Immunity, Feng et al. employed an inducible cell...
16.
Yoshida M, Worlock K, Huang N, Lindeboom R, Butler C, Kumasaka N, et al.
Nature
. 2021 Dec;
602(7896):321-327.
PMID: 34937051
It is not fully understood why COVID-19 is typically milder in children. Here, to examine the differences between children and adults in their response to SARS-CoV-2 infection, we analysed paediatric...
17.
Hatton C, Botting R, Duenas M, Haq I, Verdon B, Thompson B, et al.
Nat Commun
. 2021 Dec;
12(1):7092.
PMID: 34876592
The nasal epithelium is a plausible entry point for SARS-CoV-2, a site of pathogenesis and transmission, and may initiate the host response to SARS-CoV-2. Antiviral interferon (IFN) responses are critical...
18.
Kramer B, Knoll R, Bonaguro L, ToVinh M, Raabe J, Astaburuaga-Garcia R, et al.
Immunity
. 2021 Sep;
54(11):2650-2669.e14.
PMID: 34592166
Longitudinal analyses of the innate immune system, including the earliest time points, are essential to understand the immunopathogenesis and clinical course of coronavirus disease (COVID-19). Here, we performed a detailed...
19.
Jardine L, Webb S, Goh I, Quiroga Londono M, Reynolds G, Mather M, et al.
Nature
. 2021 Sep;
598(7880):327-331.
PMID: 34588693
Haematopoiesis in the bone marrow (BM) maintains blood and immune cell production throughout postnatal life. Haematopoiesis first emerges in human BM at 11-12 weeks after conception, yet almost nothing is...
20.
Richter A, Shields A, Karim A, Birch D, Faustini S, Steadman L, et al.
Clin Exp Immunol
. 2021 Jun;
205(2):99-105.
PMID: 34082475
Coronavirus 19 (COVID-19) has been associated with both transient and persistent systemic symptoms that do not appear to be a direct consequence of viral infection. The generation of autoantibodies has...