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Gary R Hime

Explore the profile of Gary R Hime including associated specialties, affiliations and a list of published articles. Areas
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Articles 48
Citations 517
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Recent Articles
1.
Bezawork-Geleta A, Devereux C, Keenan S, Lou J, Cho E, Nie S, et al.
Nat Commun . 2025 Mar; 16(1):2135. PMID: 40032835
Membrane contact sites between organelles are critical for the transfer of biomolecules. Lipid droplets store fatty acids and form contacts with mitochondria, which regulate fatty acid oxidation and adenosine triphosphate...
2.
Houston B, Nguyen J, Burke R, Nogueira Alves A, Hime G, OBryan M
Reproduction . 2025 Feb; 169(4). PMID: 39991973
In Brief: Hsc70Cb is essential for spermatogonia survival and sperm individualisation in Drosophila. This study highlights the conserved roles of the HSPA4 family across animals and the utility of flies...
3.
Yang Q, Wijaya F, Kapoor R, Chandrasekaran H, Jagtiani S, Moran I, et al.
Biochem Soc Trans . 2024 Nov; 52(6):2281-2295. PMID: 39508395
The growth and development of metazoan organisms is dependent upon a co-ordinated programme of cellular proliferation and differentiation, from the initial formation of the zygote through to maintenance of mature...
4.
Kline B, Siddall N, Wijaya F, Stuart C, Orlando L, Bakhshalizadeh S, et al.
Biol Reprod . 2024 Oct; 112(1):102-118. PMID: 39400047
Premature ovarian insufficiency (POI) is characterized by the loss or complete absence of ovarian activity in women under the age of 40. Clinical presentation of POI varies with phenotypic severity...
5.
Netherton J, Ogle R, Robinson B, Molloy M, Krisp C, Velkov T, et al.
iScience . 2024 Aug; 27(7):110198. PMID: 39092172
Male subfertility or infertility is a common condition often characterized by men producing a low number of sperm with poor quality. To gain insight into this condition, we performed a...
6.
Heaney J, Zhao J, Casagranda F, Loveland K, Siddall N, Hime G
Cells . 2024 Mar; 13(6. PMID: 38534338
Stem cell maintenance and differentiation can be regulated via the differential activity of transcription factors within stem cells and their progeny. For these factors to be active, they need to...
7.
Perez R, Yang X, Familari M, Martinez G, Lovicu F, Hime G, et al.
J Mol Histol . 2024 Jan; 55(1):121-138. PMID: 38165569
Differentiation of lens fiber cells involves a complex interplay of signals from growth factors together with tightly regulated gene expression via transcriptional and post-transcriptional regulators. Various studies have demonstrated that...
8.
Ayers K, Eggers S, Rollo B, Smith K, Davidson N, Siddall N, et al.
Nat Commun . 2023 Jun; 14(1):3566. PMID: 37322043
No abstract available.
9.
Ayers K, Eggers S, Rollo B, Smith K, Davidson N, Siddall N, et al.
Nat Commun . 2023 Jun; 14(1):3403. PMID: 37296101
Squamous cell carcinoma antigen recognized by T cells 3 (SART3) is an RNA-binding protein with numerous biological functions including recycling small nuclear RNAs to the spliceosome. Here, we identify recessive...
10.
Bakhshalizadeh S, Hock D, Siddall N, Kline B, Sreenivasan R, Bell K, et al.
Hum Genet . 2023 May; 142(7):879-907. PMID: 37148394
Premature ovarian insufficiency (POI) is a common cause of infertility in women, characterised by amenorrhea and elevated FSH under the age of 40 years. In some cases, POI is syndromic...