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Gary Pawlowski

Explore the profile of Gary Pawlowski including associated specialties, affiliations and a list of published articles. Areas
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Articles 7
Citations 48
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Recent Articles
1.
Laurita K, Piktel J, Irish L, Nassal M, Cheng A, McCauley M, et al.
JACC Clin Electrophysiol . 2024 May; 10(7 Pt 1):1271-1286. PMID: 38752959
Background: Ventricular tachycardia (VT)/ventricular fibrillation (VF) rearrest after successful resuscitation is common, and survival is poor. A mechanism of VT/VF, as demonstrated in ex vivo studies, is when repolarization alternans...
2.
Piktel J, Suen Y, Kouk S, Maleski D, Pawlowski G, Laurita K, et al.
J Am Heart Assoc . 2021 May; 10(10):e016676. PMID: 33938226
Background Amiodarone is administered during resuscitation, but its antiarrhythmic effects during targeted temperature management are unknown. The purpose of this study was to determine the effect of both therapeutic hypothermia...
3.
Bektik E, Dennis A, Pawlowski G, Zhou C, Maleski D, Takahashi S, et al.
Int J Mol Sci . 2018 May; 19(5). PMID: 29734659
Direct reprogramming of fibroblasts into induced cardiomyocytes (iCMs) holds a great promise for regenerative medicine and has been studied in several major directions. However, cell-cycle regulation, a fundamental biological process,...
4.
Piktel J, Cheng A, McCauley M, Dale Z, Nassal M, Maleski D, et al.
J Am Heart Assoc . 2017 Nov; 6(11). PMID: 29150491
Background: We designed an innovative porcine model of ischemia-induced arrest to determine dynamic arrhythmia substrates during focal infarct, global ischemia from ventricular tachycardia or fibrillation (VT/VF) and then reperfusion to...
5.
Tumey L, Robarge M, Gleason E, Song J, Murphy S, Ekema G, et al.
Bioorg Med Chem Lett . 2010 May; 20(11):3287-90. PMID: 20457519
CRTh2 (DP(2)) is a prostaglandin D(2) receptor implicated in the recruitment of eosinophils and basophils within the asthmatic lung. Here we report the discovery of a novel series of 3-indolyl...
6.
Anderson J, Ting A, Boozer S, Brunden K, Crumrine C, Danzig J, et al.
J Med Chem . 2005 Nov; 48(23):7096-8. PMID: 16279766
Analogues of the natural product noscapine were synthesized and their potential as antitumor agents evaluated. The discovery of a novel regioselective O-demethylation facilitated the synthesis of the potent aniline 6,...
7.
Robarge M, Bom D, Tumey L, Varga N, Gleason E, Silver D, et al.
Bioorg Med Chem Lett . 2005 Mar; 15(6):1749-53. PMID: 15745833
The chemoattractant receptor-homologous molecule expressed on T(H)2 cells (CRTH-2), also found on eosinophils and basophils, is a prostaglandin D2 receptor involved in the recruitment of these cell types during an...