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Garazi Aldanondo

Explore the profile of Garazi Aldanondo including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 113
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Recent Articles
1.
Passannante R, Gomez-Vallejo V, Sagartzazu-Aizpurua M, Vignau Arsuaga L, Marco-Moreno P, Aldanondo G, et al.
Biomedicines . 2023 Feb; 11(2). PMID: 36830793
Background And Objective: The determination of pharmacokinetic properties of new chemical entities is a key step in the process of drug development. Positron emission tomography (PET) is an ideal technique...
2.
Aizpurua J, Miranda J, Irastorza A, Torres E, Eceiza M, Sagartzazu-Aizpurua M, et al.
Eur J Med Chem . 2021 Jan; 213:113160. PMID: 33493827
The hypothesis of rescuing FKBP12/RyR1 interaction and intracellular calcium homeostasis through molecular "reshaping" of FKBP12 was investigated. To this end, novel 4-arylthioalkyl-1-carboxyalkyl-1,2,3-triazoles were designed and synthesized, and their efficacy was...
3.
Filareto A, Maguire-Nguyen K, Gan Q, Aldanondo G, Machado L, Chamberlain J, et al.
Proc Natl Acad Sci U S A . 2018 Jul; 115(30):7741-7746. PMID: 29987034
Duchenne muscular dystrophy (DMD) is a rare, muscle degenerative disease resulting from the absence of the dystrophin protein. DMD is characterized by progressive loss of muscle fibers, muscle weakness, and...
4.
Gil-Bea F, Aldanondo G, Lasa-Fernandez H, de Munain A, Vallejo-Illarramendi A
Expert Rev Mol Med . 2017 Jun; 19:e7. PMID: 28597807
Amyotrophic lateral sclerosis (ALS) is a severe neuromuscular disease characterised by a progressive loss of motor neurons that usually results in paralysis and death within 2 to 5 years after...
5.
Toral-Ojeda I, Aldanondo G, Lasa-Elgarresta J, Lasa-Fernandez H, Fernandez-Torron R, de Munain A, et al.
Expert Rev Mol Med . 2016 Apr; 18:e7. PMID: 27055500
Limb-girdle muscular dystrophy type 2A (LGMD2A) is a form of muscular dystrophy caused by mutations in calpain 3 (CAPN3). Several studies have implicated Ca2+ dysregulation as an underlying event in...
6.
Vallejo-Illarramendi A, Toral-Ojeda I, Aldanondo G, de Munain A
Expert Rev Mol Med . 2014 Oct; 16:e16. PMID: 25293420
Muscular dystrophies are a group of diseases characterised by the primary wasting of skeletal muscle, which compromises patient mobility and in the most severe cases originate a complete paralysis and...