Gang-Qing Hu
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Explore the profile of Gang-Qing Hu including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
351
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Recent Articles
1.
Zheng X, Hu G, She Z, Zhu H
BMC Genomics
. 2011 Jul;
12:361.
PMID: 21749696
Background: Shine-Dalgarno (SD) signal has long been viewed as the dominant translation initiation signal in prokaryotes. Recently, leaderless genes, which lack 5'-untranslated regions (5'-UTR) on their mRNAs, have been shown...
2.
Qi H, Sarkissian M, Hu G, Wang Z, Bhattacharjee A, Gordon D, et al.
Nature
. 2010 Jul;
466(7305):503-7.
PMID: 20622853
X-linked mental retardation (XLMR) is a complex human disease that causes intellectual disability. Causal mutations have been found in approximately 90 X-linked genes; however, molecular and biological functions of many...
3.
Luo C, Hu G, Zhu H
BMC Genomics
. 2009 Nov;
10:552.
PMID: 19930606
Background: As one of human pathogens, the genome of Uropathogenic Escherichia coli strain CFT073 was sequenced and published in 2002, which was significant in pathogenetic bacterial genomics research. However, the...
4.
Hu G, Guo J, Liu Y, Zhu H
Bioinformatics
. 2009 Apr;
25(14):1843-5.
PMID: 19389734
Summary: We proposed a tool named MetaTISA with an aim to improve TIS prediction of current gene-finders for metagenomes. The method employs a two-step strategy to predict translation initiation sites...
5.
Hu G, Zheng X, Zhu H, She Z
Bioinformatics
. 2008 Nov;
25(1):123-5.
PMID: 19015130
Unlabelled: We report a new and simple method, TriTISA, for accurate prediction of translation initiation site (TIS) of microbial genomes. TriTISA classifies all candidate TISs into three categories based on...
6.
Hu G, Zheng X, Ju L, Zhu H, She Z
BMC Bioinformatics
. 2008 Mar;
9:160.
PMID: 18366730
Background: Accurate annotation of translation initiation sites (TISs) is essential for understanding the translation initiation mechanism. However, the reliability of TIS annotation in widely used databases such as RefSeq is...
7.
Hu G, Zheng X, Yang Y, Ortet P, She Z, Zhu H
Nucleic Acids Res
. 2007 Oct;
36(Database issue):D114-9.
PMID: 17942412
Correct annotation of translation initiation site (TIS) is essential for both experiments and bioinformatics studies of prokaryotic translation initiation mechanism as well as understanding of gene regulation and gene structure....
8.
Zhu H, Hu G, Yang Y, Wang J, She Z
BMC Bioinformatics
. 2007 Mar;
8:97.
PMID: 17367537
Background: Despite a remarkable success in the computational prediction of genes in Bacteria and Archaea, a lack of comprehensive understanding of prokaryotic gene structures prevents from further elucidation of differences...
9.
Zhu H, Hu G, Ouyang Z, Wang J, She Z
Bioinformatics
. 2004 Jul;
20(18):3308-17.
PMID: 15247104
Motivation: At present the computational gene identification methods in microbial genomes have a high prediction accuracy of verified translation termination site (3' end), but a much lower accuracy of the...