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Gali Umschweif

Explore the profile of Gali Umschweif including associated specialties, affiliations and a list of published articles. Areas
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Articles 11
Citations 183
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Recent Articles
1.
Umschweif G, Medrihan L, Guillen-Samander A, Wang W, Sagi Y, Greengard P
Mol Psychiatry . 2021 Mar; 26(7):2872-2885. PMID: 33742167
Among the hallmarks of major depressive disorders (MDD) are molecular, functional, and morphological impairments in the hippocampus. Recent studies suggested a key role for hippocampal GABAergic interneurons both in depression...
2.
Umschweif G, Medrihan L, McCabe K, Sagi Y, Greengard P
Mol Psychiatry . 2021 Mar; 26(7):3350-3362. PMID: 33723417
The delayed behavioral response to chronic antidepressants depends on dynamic changes in the hippocampus. It was suggested that the antidepressant protein p11 and the chromatin remodeling factor SMARCA3 mediate this...
3.
Medrihan L, Umschweif G, Sinha A, Reed S, Lee J, Gindinova K, et al.
Biol Psychiatry . 2020 Apr; 88(5):405-414. PMID: 32331822
Background: Parvalbumin (PV)-expressing interneurons are important for cognitive and emotional behaviors. These neurons express high levels of p11, a protein associated with depression and action of antidepressants. Methods: We characterized...
4.
Umschweif G, Greengard P, Sagi Y
Eur J Neurosci . 2019 Dec; 53(1):39-64. PMID: 31811730
Extensive preclinical research has been conducted in recent years to reveal the cell types, neuronal circuits and molecular and morphological changes implicated in the function of the dentate gyrus in...
5.
Cheng J, Umschweif G, Leung J, Sagi Y, Greengard P
Neuron . 2019 Jan; 101(4):662-672.e5. PMID: 30638901
Cholinergic interneurons (ChIs) in the nucleus accumbens (NAc) have been implicated in drug addiction, reward, and mood disorders. However, the physiological role of ChIs in depression has not been characterized....
6.
Umschweif G, Shein N, Alexandrovich A, Trembovler V, Horowitz M, Shohami E
J Cereb Blood Flow Metab . 2015 Oct; 35(11):1901. PMID: 26517814
No abstract available.
7.
Horowitz M, Umschweif G, Yacobi A, Shohami E
Front Neurosci . 2015 Aug; 9:256. PMID: 26283898
Neuroprotection following prolonged exposure to high ambient temperatures (heat acclimation HA) develops via altered molecular programs such as cross-tolerance Heat Acclimation-Neuroprotection Cross-Tolerance (HANCT). The mechanisms underlying cross-tolerance depend on enhanced...
8.
Umschweif G, Liraz-Zaltsman S, Shabashov D, Alexandrovich A, Trembovler V, Horowitz M, et al.
Neurotherapeutics . 2014 Jun; 11(3):665-78. PMID: 24957202
Angiotensin II receptor type 2 (AT(2)) agonists have been shown to limit brain ischemic insult and to improve its outcome. The activation of AT(2) was also linked to induced neuronal...
9.
Umschweif G, Shabashov D, Alexandrovich A, Trembovler V, Horowitz M, Shohami E
J Cereb Blood Flow Metab . 2014 May; 34(8):1381-90. PMID: 24849663
Long-term exposure of mice to mild heat (34°C±1°C) confers neuroprotection against traumatic brain injury (TBI); however, the underling mechanisms are not fully understood. Heat acclimation (HA) increases hypothalamic angiotensin II...
10.
Umschweif G, Alexandrovich A, Trembovler V, Horowitz M, Shohami E
PLoS One . 2013 Oct; 8(10):e76129. PMID: 24124534
Preconditioning via heat acclimation (34°C 30 d) results in neuroprotection from traumatic brain injury due to constitutive as well as dynamic changes triggered by the trauma. Among these changes is...