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Gal Haimovich

Explore the profile of Gal Haimovich including associated specialties, affiliations and a list of published articles. Areas
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Articles 17
Citations 958
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Recent Articles
1.
Dasgupta S, Dayagi D, Haimovich G, Wyler E, Olender T, Singer R, et al.
Elife . 2023 May; 12. PMID: 37249209
Full-length mRNAs transfer between adjacent mammalian cells via direct cell-to-cell connections called tunneling nanotubes (TNTs). However, the extent of mRNA transfer at the transcriptome-wide level (the 'transferome') is unknown. Here,...
2.
Chattopadhyay S, Garcia-Martinez J, Haimovich G, Fischer J, Khwaja A, Barkai O, et al.
Nat Commun . 2022 Nov; 13(1):7184. PMID: 36418294
mRNA level is controlled by factors that mediate both mRNA synthesis and decay, including the 5' to 3' exonuclease Xrn1. Here we show that nucleocytoplasmic shuttling of several yeast mRNA...
3.
Nair R, Haimovich G, Gerst J
Bio Protoc . 2022 Feb; 12(1):e4274. PMID: 35118167
RNA-RNA and RNA-protein interactions are involved in the regulation of gene expression. Here, we describe an updated and extended version of our RNA purification and protein identification (RaPID) protocol for...
4.
Haimovich G, Gerst J
Bio Protoc . 2021 Sep; 8(21):e3070. PMID: 34532531
Transcription and RNA decay play critical roles in the process of gene expression and the ability to accurately measure cellular mRNA levels is essential for understanding this regulation. Here, we...
5.
Haimovich G, Dasgupta S, Gerst J
Biochem Soc Trans . 2020 Dec; 49(1):145-160. PMID: 33367488
It was already suggested in the early '70's that RNA molecules might transfer between mammalian cells in culture. Yet, more direct evidence for RNA transfer in animal and plant cells...
6.
Haimovich G, Gerst J
Methods Mol Biol . 2019 Aug; 2038:109-129. PMID: 31407281
In eukaryotic cells, a small percentage of mRNA molecules can undergo transfer from one cell to another. mRNA transfer occurs primarily via membrane nanotubes, which are long thin protrusions that...
7.
Haimovich G, Ecker C, Dunagin M, Eggan E, Raj A, Gerst J, et al.
Proc Natl Acad Sci U S A . 2017 Oct; 114(46):E9873-E9882. PMID: 29078295
RNAs have been shown to undergo transfer between mammalian cells, although the mechanism behind this phenomenon and its overall importance to cell physiology is not well understood. Numerous publications have...
8.
Haimovich G, Zabezhinsky D, Haas B, Slobodin B, Purushothaman P, Fan L, et al.
RNA . 2016 Mar; 22(5):660-6. PMID: 26968626
The MS2 system has been extensively used to visualize single mRNA molecules in live cells and follow their localization and behavior. In their Letter to the Editor recently published, Garcia...
9.
Haimovich G, Cohen-Zontag O, Gerst J
Biochim Biophys Acta . 2015 Sep; 1863(5):911-21. PMID: 26367800
Peroxisomes are distinct membrane-enclosed organelles involved in the β-oxidation of fatty acids and synthesis of ether phospholipids (e.g. plasmalogens), as well as cholesterol and its derivatives (e.g. bile acids). Peroxisomes...
10.
Buxbaum A, Haimovich G, Singer R
Nat Rev Mol Cell Biol . 2015 Jan; 16(2):95-109. PMID: 25549890
The spatial regulation of protein translation is an efficient way to create functional and structural asymmetries in cells. Recent research has furthered our understanding of how individual cells spatially organize...