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Gaetan Mayer

Explore the profile of Gaetan Mayer including associated specialties, affiliations and a list of published articles. Areas
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Articles 33
Citations 1217
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Recent Articles
1.
Briere R, Emond M, Benhamed A, Blanchard P, Golbon B, Shellenberger J, et al.
Can J Surg . 2024 Jan; 66(6 Suppl 1):S54-S136. PMID: 38173057
No abstract available.
2.
Vachon L, Smaani A, Tessier N, Jean G, Demers A, Milasan A, et al.
Theranostics . 2022 Feb; 12(3):1440-1458. PMID: 35154499
Impairment in lymphatic transport is associated with the onset and progression of atherosclerosis in animal models. The downregulation of low-density-lipoprotein receptor (LDLR) expression, rather than increased circulating cholesterol level ,...
3.
Vourakis M, Mayer G, Rousseau G
Int J Mol Sci . 2021 Aug; 22(15). PMID: 34360839
Hypercholesterolemia plays a causal role in the development of atherosclerosis and is one of the main risk factors for cardiovascular disease (CVD), the leading cause of death worldwide especially in...
4.
Cyr Y, Lamantia V, Bissonnette S, Burnette M, Besse-Patin A, Demers A, et al.
Physiol Rep . 2021 Feb; 9(3):e14721. PMID: 33527668
Background: LDL-cholesterol lowering variants that upregulate receptor uptake of LDL, such as in PCSK9 and HMGCR, are associated with diabetes via unclear mechanisms. Activation of the NLRP3 inflammasome/interleukin-1 beta (IL-1β)...
5.
Cyr Y, Bissonnette S, Lamantia V, Wassef H, Loizon E, Ngo Sock E, et al.
Obesity (Silver Spring) . 2020 Oct; 28(12):2357-2367. PMID: 33043593
Objective: Human conditions with upregulated receptor uptake of low-density lipoproteins (LDL) are associated with diabetes risk, the reasons for which remain unexplored. LDL induce metabolic dysfunction in murine adipocytes. Thus,...
6.
Pasquin S, Laplante V, Kouadri S, Milasan A, Mayer G, Tormo A, et al.
J Immunol . 2018 Sep; 201(8):2462-2471. PMID: 30209193
CLCF1 is a neurotrophic and B cell-stimulating factor belonging to the IL-6 family. Mutations in the gene coding for CLCF1 or its secretion partner CRLF1 lead to the development of...
7.
Rautureau Y, Deschambault V, Higgins M, Rivas D, Mecteau M, Geoffroy P, et al.
Circulation . 2018 Apr; 138(16):1677-1692. PMID: 29674325
Background: Pharmacogenomic studies have shown that ADCY9 genotype determines the effects of the CETP (cholesteryl ester transfer protein) inhibitor dalcetrapib on cardiovascular events and atherosclerosis imaging. The underlying mechanisms responsible...
8.
Pasquin S, Chehboun S, Dejda A, Meliani Y, Savin V, Warner G, et al.
Sci Rep . 2018 Mar; 8(1):3990. PMID: 29507344
The cytokines CLCF1 and CNTF are ligands for the CNTF receptor and the apolipoprotein E (ApoE) receptor sortilin. Both share structural similarities with the N-terminal domain of ApoE, known to...
9.
Mnasri N, Mamarbachi M, Allen B, Mayer G
Biochim Biophys Acta Gene Regul Mech . 2017 Dec; 1861(1):29-40. PMID: 29208426
Hepatic low-density lipoprotein receptor (LDLR) is the primary conduit for the clearance of plasma LDL-cholesterol and increasing its expression represents a central goal for treating cardiovascular disease. However, LDLR mRNA...
10.
Segura E, Bourdin B, Tetreault M, Briot J, Allen B, Mayer G, et al.
J Biol Chem . 2017 May; 292(26):11109-11124. PMID: 28495885
Voltage-gated L-type Ca1.2 channels in cardiomyocytes exist as heteromeric complexes with the pore-forming Caα1, Caβ, and Caα2δ1 subunits. The full complement of subunits is required to reconstitute the native-like properties...