Gaelle Rondeau
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Explore the profile of Gaelle Rondeau including associated specialties, affiliations and a list of published articles.
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17
Citations
251
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Recent Articles
1.
Chrastina A, Welsh J, Rondeau G, Abedinpour P, Borgstrom P, Baron V
ChemMedChem
. 2020 May;
15(14):1338-1347.
PMID: 32410390
Plumbagin (5-hydroxy-2-methyl-1,4-naphthoquinone) is a small molecule with potent anticancer activity. Like other 1,4-naphthoquinones, it exhibits electrophilic reactivity towards biological nucleophiles. We demonstrate that plumbagin and structurally related 1,4-naphthoquinones with at...
2.
Chrastina A, Baron V, Abedinpour P, Rondeau G, Welsh J, Borgstrom P
Biomed Res Int
. 2018 Dec;
2018:9035452.
PMID: 30534567
Background: Plumbagin, a medicinal plant-derived 5-hydroxy-2-methyl-1,4-naphthoquinone, is an emerging drug with a variety of pharmacological effects, including potent anticancer activity. We have previously shown that plumbagin improves the efficacy of...
3.
Rondeau G, Abedinpour P, Chrastina A, Pelayo J, Borgstrom P, Welsh J
Sci Rep
. 2018 Feb;
8(1):2694.
PMID: 29426892
Treatment of mice harboring PTEN-P2 tumors in the prostate or on prostate tissue in vivo with 5-hydroxy-2-methyl-1,4-naphthoquinone, also known as plumbagin, results in tumor regression in castrated mice, but not...
4.
Abedinpour P, Baron V, Chrastina A, Rondeau G, Pelayo J, Welsh J, et al.
Prostate
. 2017 Oct;
77(16):1550-1562.
PMID: 28971491
Background: Plumbagin is a candidate drug for the treatment of prostate cancer. Previous observations indicated that it may improve the efficacy of androgen deprivation therapy (ADT). This study evaluates the...
5.
Rondeau G, Abedinpour P, Desai P, Baron V, Borgstrom P, Welsh J
PLoS One
. 2014 Jul;
9(7):e101160.
PMID: 25004123
In metastasis, circulating tumor cells penetrate the walls of blood vessels and enter the metastatic target tissue, thereby becoming exposed to novel and relatively unsupportive microenvironments. In the new microenvironments,...
6.
Chandra M, Cheng P, Rondeau G, Porwollik S, McClelland M
Int J Med Microbiol
. 2013 Apr;
303(4):210-6.
PMID: 23562277
E. coli is generally a commensal but includes some highly pathogenic strains carrying additional genes in plasmids and/or the chromosome. Based on these genes the pathogenic strains are divided into...
7.
Wu X, Chesoni S, Rondeau G, Tempesta C, Patel R, Charles S, et al.
Nucleic Acids Res
. 2013 Jan;
41(4):2644-58.
PMID: 23303783
The RNA-binding protein AUF1 binds AU-rich elements in 3'-untranslated regions to regulate mRNA degradation and/or translation. Many of these mRNAs are predicted microRNA targets as well. An emerging theme in...
8.
Bie L, Zhao G, Cheng P, Rondeau G, Porwollik S, Ju Y, et al.
PLoS One
. 2011 Oct;
6(10):e25631.
PMID: 22022424
Identification of gene expression changes that improve prediction of survival time across all glioma grades would be clinically useful. Four Affymetrix GeneChip datasets from the literature, containing data from 771...
9.
Frye J, Lindsey R, Rondeau G, Porwollik S, Long F, McClelland M, et al.
Microb Drug Resist
. 2009 Nov;
16(1):9-19.
PMID: 19916789
To understand the mechanisms and epidemiology of antimicrobial resistance (AR), the genetic elements responsible must be identified. Due to the myriad of possible genes, a high-density genotyping technique is needed...
10.
Risques R, Rondeau G, Judex M, McClelland M, Welsh J
Nucleic Acids Res
. 2008 May;
36(10):e60.
PMID: 18474526
Microarrays and high-throughput sequencing methods can be used to measure the expression of thousands of genes in a biological sample in a few days, whereas PCR-based methods can be used...