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Gabrielle Smith

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Articles 17
Citations 140
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Recent Articles
1.
Xu M, Tourigny D, Lippert J, Crastin A, Appenzeller S, Asia M, et al.
J Endocrinol Invest . 2025 Feb; PMID: 39891827
Background: Somatic alterations are commonly observed in adrenocortical adenomas including cortisol-producing (CPA) [overt Cushing syndrome (CS) or mild autonomous cortisol secretion (MACS)], aldosterone-producing (APA), and non-functioning (NFAT) tumors. We tested...
2.
Chakraverty R, Kempshall E, Dignan F, Bloor A, Collin M, Raj K, et al.
BMJ Open . 2025 Jan; 15(1):e086223. PMID: 39880444
Introduction: Graft-versus-host disease (GvHD) remains a major complication of allogeneic stem cell transplantation (allo-SCT), affecting 30-70% of patients (representing 800 new patients per year in the UK). The risk is...
3.
Kaszyk E, Commean P, Meyer G, Smith G, Jeong H, York A, et al.
Gait Posture . 2024 May; 112:159-166. PMID: 38797052
Background: Decreased muscle volume and increased muscle-associated adipose tissue (MAAT, sum of intra and inter-muscular adipose tissue) of the foot intrinsic muscle compartment are associated with deformity, decreased function, and...
4.
Moore-Harrison T, Keane K, Brandon L, Smith G, Brown C
Am J Health Promot . 2024 Apr; 38(7):1029-1032. PMID: 38581257
Purpose: This study evaluated the impact of obesity on cardiometabolic risk factors (CRF) interrelationships and predictive efficiency of CVD development in older African (AA) and European Americans (EA). Design: A...
5.
Lippert J, Smith G, Appenzeller S, Landwehr L, Prete A, Steinhauer S, et al.
Eur J Endocrinol . 2024 Mar; 190(3):234-247. PMID: 38451242
Objective: Adrenocortical carcinoma (ACC) is a rare aggressive cancer with heterogeneous behaviour. Disease surveillance relies on frequent imaging, which comes with significant radiation exposure. The aim of the study was...
6.
Warmington E, Smith G, Chortis V, Liang R, Lippert J, Steinhauer S, et al.
Endocr Connect . 2023 Nov; 13(1). PMID: 37992487
Adrenocortical carcinoma (ACC) is an aggressive malignancy with limited treatment options. Polo-like kinase 1 (PLK1) is a promising drug target; PLK1 inhibitors (PLK1i) have been investigated in solid cancers and...
7.
Lippert J, Altieri B, Morrison B, Steinhauer S, Smith G, Lorey A, et al.
J Clin Endocrinol Metab . 2022 Aug; 107(10):2892-2899. PMID: 35929659
Context: Adrenocortical carcinoma (ACC) is a rare aggressive disease with heterogeneous prognoses. Previous studies identified hypermethylation in the promoter region of specific genes to be associated with poor clinical outcome....
8.
Nasteska D, Fine N, Ashford F, Cuozzo F, Viloria K, Smith G, et al.
Nat Commun . 2021 Jul; 12(1):4521. PMID: 34285239
No abstract available.
9.
Westgate C, Botfield H, Alimajstorovic Z, Yiangou A, Walsh M, Smith G, et al.
JCI Insight . 2021 Apr; 6(10). PMID: 33848268
BACKGROUNDIdiopathic intracranial hypertension (IIH) is a condition predominantly affecting obese women of reproductive age. Recent evidence suggests that IIH is a disease of metabolic dysregulation, androgen excess, and an increased...
10.
Nasteska D, Fine N, Ashford F, Cuozzo F, Viloria K, Smith G, et al.
Nat Commun . 2021 Jan; 12(1):674. PMID: 33514698
Transcriptionally mature and immature β-cells co-exist within the adult islet. How such diversity contributes to insulin release remains poorly understood. Here we show that subtle differences in β-cell maturity, defined...