Silke Appenzeller
Overview
Explore the profile of Silke Appenzeller including associated specialties, affiliations and a list of published articles.
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60
Citations
923
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Recent Articles
1.
Xu M, Tourigny D, Lippert J, Crastin A, Appenzeller S, Asia M, et al.
J Endocrinol Invest
. 2025 Feb;
PMID: 39891827
Background: Somatic alterations are commonly observed in adrenocortical adenomas including cortisol-producing (CPA) [overt Cushing syndrome (CS) or mild autonomous cortisol secretion (MACS)], aldosterone-producing (APA), and non-functioning (NFAT) tumors. We tested...
2.
Gotz L, Wegert J, Paikari A, Appenzeller S, Bausenwein S, Vokuhl C, et al.
Transl Oncol
. 2024 Dec;
52():102263.
PMID: 39740515
Wilms tumors (WT) are characterized by variable contributions of blastemal, epithelial and stromal elements, reflecting their diverse cellular origins and genetic drivers. In vitro models remain rare, despite a growing...
3.
Menzel M, Martis-Thiele M, Goldschmid H, Ott A, Romanovsky E, Siemanowski-Hrach J, et al.
Eur J Cancer
. 2024 Sep;
211:114306.
PMID: 39293347
Introduction: Whole Exome Sequencing (WES) has emerged as an efficient tool in clinical cancer diagnostics to broaden the scope from panel-based diagnostics to screening of all genes and enabling robust...
4.
Elhassan Y, Appenzeller S, Landwehr L, Lippert J, Popat D, Gilligan L, et al.
Eur J Endocrinol
. 2024 Aug;
191(3):334-344.
PMID: 39171930
Background: Primary bilateral macronodular adrenal hyperplasia (PBMAH) is a rare cause of Cushing's syndrome. Individuals with PBMAH and glucose-dependent insulinotropic polypeptide (GIP)-dependent Cushing's syndrome due to ectopic expression of the...
5.
Deschler-Baier B, Krebs M, Kroiss M, Chatterjee M, Gundel D, Kestler C, et al.
NPJ Precis Oncol
. 2024 Jul;
8(1):167.
PMID: 39085487
This case report describes the efficacy of selpercatinib, a selective RET inhibitor, in an unusual case of large-cell neuroendocrine pancreatic carcinoma (LCNEPAC) harboring a CCDC6::RET fusion. A 56-year-old male with...
6.
Kervarrec T, Appenzeller S, Gramlich S, Coyaud E, Bachiri K, Appay R, et al.
J Pathol
. 2024 Jul;
264(1):112-124.
PMID: 39049595
Merkel cell carcinoma (MCC) is an aggressive skin cancer frequently caused by genomic integration of the Merkel cell polyomavirus (MCPyV). MCPyV-negative cases often present as combined MCCs, which represent a...
7.
Wobser M, Appenzeller S, Roth S, Siedel C, Goebeler M, Geissinger E, et al.
Br J Dermatol
. 2024 Jun;
191(5):816-822.
PMID: 38924750
Background: Primary cutaneous acral CD8+ T-cell lymphoproliferative disorder (TLPD) is a rare and indolent lymphoma entity. Although TLPD was first identified many years ago, the molecular pathogenesis is still not...
8.
Lippert J, Smith G, Appenzeller S, Landwehr L, Prete A, Steinhauer S, et al.
Eur J Endocrinol
. 2024 Mar;
190(3):234-247.
PMID: 38451242
Objective: Adrenocortical carcinoma (ACC) is a rare aggressive cancer with heterogeneous behaviour. Disease surveillance relies on frequent imaging, which comes with significant radiation exposure. The aim of the study was...
9.
Duell J, Leipold A, Appenzeller S, Fuhr V, Rauert-Wunderlich H, Da Via M, et al.
Blood
. 2023 Nov;
143(8):685-696.
PMID: 37976456
CD19 chimeric antigen receptor (CAR) T cells and CD20 targeting T-cell-engaging bispecific antibodies (bispecs) have been approved in B-cell non-Hodgkin lymphoma lately, heralding a new clinical setting in which patients...
10.
Kervarrec T, Appenzeller S, Tallet A, Jullie M, Sohier P, Guillonneau F, et al.
Histopathology
. 2023 Oct;
84(2):356-368.
PMID: 37830288
Aims: Merkel cell carcinoma (MCC) is frequently caused by the Merkel cell polyomavirus (MCPyV). Characteristic for these virus-positive (VP) MCC is MCPyV integration into the host genome and truncation of...