Gabriele Multhoff
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Explore the profile of Gabriele Multhoff including associated specialties, affiliations and a list of published articles.
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241
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8608
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Recent Articles
1.
Seitz S, Dreyer T, Stange C, Steiger K, Wohlleber D, Anton M, et al.
Neoplasia
. 2025 Jan;
60:101130.
PMID: 39862711
T-cell recruiting chemokines are required for a successful immune intervention in ovarian cancer, and also for the efficacy of modern anticancer agents such as PARP inhibitors. The chemokine CX3CL1 recruits...
2.
Alkotub B, Bauer L, Bashiri Dezfouli A, Hachani K, Ntziachristos V, Multhoff G, et al.
Redox Biol
. 2024 Dec;
79():103452.
PMID: 39667305
Despite advances in multimodal therapy approaches such as resection, chemotherapy and radiotherapy, the overall survival of patients with grade 4 glioblastoma (GBM) remains extremely poor (average survival time <2 years)....
3.
Guder C, Heinrich S, Seifert-Klauss V, Kiechle M, Bauer L, Ollinger R, et al.
Int J Mol Sci
. 2024 Nov;
25(21).
PMID: 39519195
Stress-inducible heat shock protein 70 (Hsp70), which functions as a molecular chaperone and is frequently overexpressed in different cancer cell types, is present on the cell surface of tumor cells...
4.
Bauer L, Alkotub B, Ballmann M, Kafshgari M, Rammes G, Multhoff G
Cancers (Basel)
. 2024 Nov;
16(21).
PMID: 39518030
Radiotherapy, which is commonly used for the local control of thoracic cancers, also induces chronic inflammatory responses in the microvasculature of surrounding normal tissues such as the lung and heart...
5.
Holzmann K, Wolf J, Stangl S, Lennartz P, Kasajima A, Mogler C, et al.
Br J Cancer
. 2024 Oct;
131(11):1814-1824.
PMID: 39406917
Background: The primary goal of surgery in HNSCC is the complete resection of tumor cells with maximum preservation of normal tissue. The membrane Hsp70-targeting fluorescence labelled peptide TPP-IRDye800 represents a...
6.
Hoch C, Hachani K, Han Y, Schmidl B, Wirth M, Multhoff G, et al.
Expert Opin Biol Ther
. 2024 Sep;
24(10):1057-1073.
PMID: 39291462
Introduction: Head and neck cancer (HNC), primarily head and neck squamous cell carcinomas, originates from the squamous epithelium in areas like the oral cavity, lip, larynx, and oropharynx. With high...
7.
Wang F, Bashiri Dezfouli A, Multhoff G
Mol Immunol
. 2024 Aug;
174:1-10.
PMID: 39126837
Background: Cannabidiol (CBD), the major non-psychoactive component of cannabis, exhibits anti-inflammatory properties, but less is known about the immunomodulatory potential of CBD on activated natural killer (NK) cells and/or their...
8.
Muhtadi R, Bernhardt D, Multhoff G, Honikl L, Combs S, Krieg S, et al.
Cancers (Basel)
. 2024 Jul;
16(13).
PMID: 39001407
GBM WHO CNS Grade 4 represents a major challenge for oncology due to its aggressive behavior. Conventional imaging has restrictions in detecting tumor recurrence. This prospective study aims to identify...
9.
Yazdi M, Pohmerer J, Kafshgari M, Seidl J, Grau M, Hohn M, et al.
Small
. 2024 Jun;
20(42):e2400643.
PMID: 38923700
Although small-interfering RNAs (siRNAs) are specific silencers for numerous disease-related genes, their clinical applications still require safe and effective means of delivery into target cells. Highly efficient lipid nanoparticles (LNPs)...
10.
Hoch C, Shoykhet M, Weiser T, Griesbaum L, Petry J, Hachani K, et al.
Pharmacol Res
. 2024 Feb;
201:107107.
PMID: 38354869
In recent years, isothiocyanates (ITCs), bioactive compounds primarily derived from Brassicaceae vegetables and herbs, have gained significant attention within the biomedical field due to their versatile biological effects. This comprehensive...