Gabriel W Rangel
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Explore the profile of Gabriel W Rangel including associated specialties, affiliations and a list of published articles.
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13
Citations
173
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Recent Articles
1.
Mamede L, Rangel G, Shinyuy L, Boussif N, Herent M, Govaerts B, et al.
Phytomedicine
. 2025 Jan;
136():156361.
PMID: 39765035
Background: Artemisia spp. have been used for millennia in traditional medicine to treat a variety of ailments, including malaria. Extracts of Artemisia afra and A. annua remain widely used throughout...
2.
Rajaram K, Rangel G, Munro J, Nair S, Llinas M, Prigge S
bioRxiv
. 2024 Dec;
PMID: 39651245
Significance: The mitochondrion of malaria parasites generates key molecules, such as acetyl-CoA, that are required for numerous cellular processes. To support mitochondrial biosynthetic pathways, the parasites must transport carbon sources...
3.
Hagenah L, Dhingra S, Small-Saunders J, Qahash T, Willems A, Schindler K, et al.
mBio
. 2023 Dec;
15(1):e0183223.
PMID: 38059639
Our study leverages gene editing techniques in asexual blood stage parasites to profile novel mutations in mutant PfCRT, an important mediator of piperaquine resistance, which developed in Southeast Asian field...
4.
Ansah E, Moucheraud C, Arogundade L, Rangel G
PLOS Glob Public Health
. 2023 Mar;
2(6):e0000462.
PMID: 36962405
Despite worldwide efforts and much progress toward malaria control, declines in malaria morbidity and mortality have hit a plateau. While many nations achieved significant malaria suppression or even elimination, success...
5.
Rangel G, Llinas M
Front Cell Infect Microbiol
. 2021 Jun;
11:691121.
PMID: 34178727
Parasites of the phylum Apicomplexa impact humans in nearly all parts of the world, causing diseases including to toxoplasmosis, cryptosporidiosis, babesiosis, and malaria. Apicomplexan parasites have complex life cycles comprised...
6.
Clark M, Kanjee U, Rangel G, Chery L, Mascarenhas A, Gomes E, et al.
Nat Commun
. 2021 Mar;
12(1):1629.
PMID: 33712609
The structural integrity of the host red blood cell (RBC) is crucial for propagation of Plasmodium spp. during the disease-causing blood stage of malaria infection. To assess the stability of...
7.
Monitoring Plasmodium vivax resistance to antimalarials: Persisting challenges and future directions
Ferreira M, Nobrega de Sousa T, Rangel G, Johansen I, Corder R, Ladeia-Andrade S, et al.
Int J Parasitol Drugs Drug Resist
. 2020 Dec;
15:9-24.
PMID: 33360105
Emerging antimalarial drug resistance may undermine current efforts to control and eliminate Plasmodium vivax, the most geographically widespread yet neglected human malaria parasite. Endemic countries are expected to assess regularly...
8.
Kanjee U, Gruring C, Babar P, Meyers A, Dash R, Pereira L, et al.
J Infect Dis
. 2020 Sep;
223(10):1817-1821.
PMID: 32941614
Plasmodium vivax has 2 invasion ligand/host receptor pathways (P. vivax Duffy-binding protein/Duffy antigen receptor for chemokines [DARC] and P. vivax reticulocyte binding protein 2b/transferrin receptor [TfR1]) that are promising targets...
9.
Hung J, Goodman A, Ravel D, Lopes S, Rangel G, Nery O, et al.
BMC Bioinformatics
. 2020 Jul;
21(1):300.
PMID: 32652926
Background: A common yet still manual task in basic biology research, high-throughput drug screening and digital pathology is identifying the number, location, and type of individual cells in images. Object...
10.
Rangel G, Clark M, Kanjee U, Goldberg J, MacInnis B, Jose Menezes M, et al.
PLoS Negl Trop Dis
. 2020 Mar;
14(3):e0008104.
PMID: 32119669
Approximately one-third of the global population is at risk of Plasmodium vivax infection, and an estimated 7.51 million cases were reported in 2017. Although, P. vivax research is currently limited...