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Gabriel Bellavance

Explore the profile of Gabriel Bellavance including associated specialties, affiliations and a list of published articles. Areas
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Articles 8
Citations 59
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Recent Articles
1.
Hebert M, Bellavance G, Barriault L
J Am Chem Soc . 2022 Sep; 144(39):17792-17796. PMID: 36150149
Ginkgolides are diterpenes isolated from that exhibit strong anti-inflammatory and neuroprotective properties. The highly complex molecular architecture of ginkgolides, combined with their remarkable biological profile, provides a unique platform for...
2.
Nicolaou K, Buchman M, Bellavance G, Krieger J, Subramanian P, Kumar Pulukuri K
J Org Chem . 2018 Oct; 83(20):12374-12389. PMID: 30277774
Modular syntheses of disorazoles A and B analogues in which the epoxide moieties of the natural products were replaced with cyclopropyl units have been achieved. Targeted as part of a...
3.
Bellavance G, Barriault L
J Org Chem . 2018 May; 83(13):7215-7230. PMID: 29732886
The remarkable biological activities of polyprenylated polycyclic acylphloroglucinols (PPAPs) combined with their highly oxygenated and densely functionalized frameworks have stimulated the interest of synthetic organic chemists over the past decade....
4.
Nicolaou K, Bellavance G, Buchman M, Kumar Pulukuri K
J Am Chem Soc . 2017 Oct; 139(44):15636-15639. PMID: 29064682
Described herein are the first total syntheses of naturally occurring antitumor agents disorazoles A and B and the full structural assignment of the latter. The syntheses were achieved through convergent...
5.
McGee P, Bellavance G, Korobkov I, Tarasewicz A, Barriault L
Chemistry . 2015 Jun; 21(27):9662-5. PMID: 26037504
During our efforts toward the synthesis of naturally occurring polyprenylated polycyclic acylphloroglucinol using a Au(I)-catalyzed 6-endo dig carbocyclization, we isolated stable vinyllic gold intermediates. Optimization lead to isolated yields of...
6.
Bellavance G, Barriault L
Angew Chem Int Ed Engl . 2014 May; 53(26):6701-4. PMID: 24838522
The remarkable biological activities of polyprenylated polycyclic acylphloroglucinols (PPAPs) combined with their highly decorated bicyclo[3.3.1]nonane-2,4,9-trione frameworks have inspired synthetic organic chemists over the last decade. The concise total syntheses of...
7.
Sow B, Bellavance G, Barabe F, Barriault L
Beilstein J Org Chem . 2011 Sep; 7:1007-13. PMID: 21915201
The rapid synthesis of bicyclo[m.n.1]alkanone cores possessing quaternary carbon centers adjacent to a bridged ketone represents a significant synthetic challenge. This type of architectural feature is embedded in various complex...
8.
Barabe F, Betournay G, Bellavance G, Barriault L
Org Lett . 2009 Sep; 11(18):4236-8. PMID: 19739690
Bicyclo[m.n.1]alkenone frameworks possessing quaternary carbon centers adjacent to a bridged ketone are frequently found in bioactive natural products. Although several methods have been developed to construct such frameworks, most of...