Gabriel A Cook
Overview
Explore the profile of Gabriel A Cook including associated specialties, affiliations and a list of published articles.
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17
Citations
240
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Recent Articles
1.
Harris M, Dolan R, Bryce J, Ewusi J, Cook G
ACS Omega
. 2023 Nov;
8(43):40904-40910.
PMID: 37929139
Membrane glycoproteins are proteins that reside in the membranes of cells and are post-translationally modified to have sugars attached to their amino acid side chains. Studies of this subset of...
2.
Anderson A, Cook G
Protein Expr Purif
. 2022 Sep;
201:106170.
PMID: 36179942
Syndecan-1 (SDC-1) is an integral membrane heparin sulfate proteoglycan that is involved in inflammatory response, cell-signaling, cell proliferation, and numerous other cell-matrix interactions. Like the other members of the syndecan...
3.
Ahangama Liyanage L, Harris M, Cook G
ACS Omega
. 2021 May;
6(18):12133-12142.
PMID: 34056367
Glycoproteins are post-translationally modified proteins that take part in nearly every biological process and make up a large percent of the proteome. N-Linked glycosylation can be performed by -glycosyltransferase (NGT),...
4.
Jamaleddine M, Harris M, Liyanage L, Cook G
Protein Expr Purif
. 2019 Nov;
167:105525.
PMID: 31682967
Mutation of the gene encoding γ-sarcoglycan (SGCG), an integral membrane protein responsible for maintaining the integrity of the muscle cell sarcolemma, results in Limb-Girdle Muscular Dystrophy (LGMD), a congenital disease...
5.
Cook G, Dawson L, Tian Y, Opella S
Biochemistry
. 2013 Jul;
52(31):5295-303.
PMID: 23841474
Hepatitis C virus (HCV) protein p7 plays an important role in the assembly and release of mature virus particles. This small 63-residue membrane protein has been shown to induce channel...
6.
Son W, Park S, Nothnagel H, Lu G, Wang Y, Zhang H, et al.
J Magn Reson
. 2011 Nov;
214(1):111-8.
PMID: 22079194
'q-Titration' refers to the systematic comparison of signal intensities in solution NMR spectra of uniformly (15)N labeled membrane proteins solubilized in micelles and isotropic bicelles as a function of the...
7.
Park S, Berkamp S, Cook G, Chan M, Viadiu H, Opella S
Biochemistry
. 2011 Sep;
50(42):8983-5.
PMID: 21936505
It is challenging to find membrane mimics that stabilize the native structures, dynamics, and functions of membrane proteins. In a recent advance, nanodiscs have been shown to provide a bilayer...
8.
Cook G, Opella S
Biochim Biophys Acta
. 2010 Aug;
1808(6):1448-53.
PMID: 20727850
P7 is a small membrane protein that is essential for the infectivity of hepatitis C virus. Solution-state NMR experiments on p7 in DHPC micelles, including hydrogen/deuterium exchange, paramagnetic relaxation enhancement...
9.
Cook G, Zhang H, Park S, Wang Y, Opella S
Biochim Biophys Acta
. 2010 Aug;
1808(2):554-60.
PMID: 20727848
The p7 protein from hepatitis C virus and the Vpu protein from HIV-1 are members of the viroporin family of small viral membrane proteins. It is essential to determine their...
10.
Cook G, Stefer S, Opella S
Biopolymers
. 2010 Jun;
96(1):32-40.
PMID: 20560141
A small 63-residue membrane protein, p7, has essential roles in the infectivity of the hepatitis C virus in humans. This hydrophobic membrane protein forms homo-oligomeric ion channels in bilayers, which...