G Wurthwein
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Explore the profile of G Wurthwein including associated specialties, affiliations and a list of published articles.
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16
Citations
237
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Recent Articles
1.
Vehreschild J, Heussel C, Groll A, Vehreschild M, Silling G, Wurthwein G, et al.
Eur Radiol
. 2017 Jan;
27(8):3275-3282.
PMID: 28083695
Background: Serial chest CT is the standard of care to establish treatment success in invasive pulmonary aspergillosis (IPA). Data are lacking how response should be defined. Methods: Digital CT images...
2.
Cornely O, Vehreschild J, Vehreschild M, Wurthwein G, Arenz D, Schwartz S, et al.
Antimicrob Agents Chemother
. 2011 Sep;
55(12):5798-803.
PMID: 21911573
Our objective was to evaluate the maximum tolerated dose of caspofungin for invasive aspergillosis (IA). The safety and pharmacokinetics of escalating dosages of caspofungin were investigated in IA. Eight patients...
3.
Koling S, Hempel G, Lanvers C, Boos J, Wurthwein G
Int J Clin Pharmacol Ther
. 2007 Oct;
45(9):496-503.
PMID: 17907592
Introduction: Paracetamol (PCM) is frequently used in pediatric patients with neoplastic disease. It is metabolized mainly by conjugation, but at therapeutic concentrations, a small fraction of the drug undergoes oxidative...
4.
Muhlisch J, Bajanowski T, Rickert C, Roggendorf W, Wurthwein G, Jurgens H, et al.
J Neurooncol
. 2007 Jan;
83(1):17-29.
PMID: 17206475
Certain risk groups among tumors of the central nervous system (CNS) in children take an almost inevitably fatal course. The elucidation of molecular mechanisms offers hope for improved therapy. Aberrant...
5.
Lanvers-Kaminsky C, Krefeld B, Dinnesen A, Deuster D, Seifert E, Wurthwein G, et al.
Pediatr Blood Cancer
. 2005 Nov;
47(2):183-93.
PMID: 16302218
Background: To overcome the ototoxicity of cisplatin, single bolus infusions were replaced by repeated prolonged infusions of lower doses or by continuous infusions at still lower infusion rates. However, considering...
6.
Vieira Pinheiro J, Wenner K, Escherich G, Lanvers-Kaminsky C, Wurthwein G, Janka-Schaub G, et al.
Pediatr Blood Cancer
. 2005 Jun;
46(1):18-25.
PMID: 15929133
Background And Procedure: Pharmacological surrogate parameters are considered a useful tool in estimating the treatment intensity of asparaginase (ASNase) preparations. When a pegylated ASNase (single infusion of 2,500 IU/m(2) polyethylene...
7.
Vieira Pinheiro J, Lanversa C, Wurthwein G, Beier R, Casimiro da Palma J, von Stackelberg A, et al.
Leuk Lymphoma
. 2002 Dec;
43(10):1911-20.
PMID: 12481884
This is an updated review of the pharmacokinetic profile of PEG-asparaginase (PEG-ASNase) in childhood acute lymphoblastic leukemia (ALL) or non-Hodgkin's lymphoma (NHL). In a total of 271 children undergoing ALL/NHL...
8.
Vieira Pinheiro J, Muller H, Schwabe D, Gunkel M, Casimiro da Palma J, Henze G, et al.
Br J Haematol
. 2001 May;
113(1):115-9.
PMID: 11328290
Use of asparaginase (ASNase) in the treatment of relapsed childhood acute lymphoblastic leukaemia (ALL) is associated with a high rate of hypersensitive reactions. 'Silent' inactivation may additionally reduce treatment intensity....
9.
Wurthwein G, Boos J
Anticancer Drugs
. 2001 Mar;
12(2):151-8.
PMID: 11261889
It is the aim of this study to establish a simulation tool for etoposide (Eto) which can be used to interpret drug monitoring data in clinical practice and to design...
10.
Dubbers A, Wurthwein G, Muller H, Winkelhorst M, Kurzknabe E, Lanvers C, et al.
Br J Haematol
. 2000 Jun;
109(2):427-9.
PMID: 10848836
Lack of sufficient cellular activity of asparagine synthetase (AS) in blast cells compared with normal tissue is thought to be the basis of the antileukaemic effect of L-asparaginase in acute...