Alpha 2.0
Login Register
» Authors » G U Mallikarjuna

G U Mallikarjuna

Explore the profile of G U Mallikarjuna including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 6
Citations 151
Followers 0
Related Specialties
Oncology
Biochemistry
Top 10 Co-Authors
Sivanandhan Dhanalakshmi
Rajesh Agarwal
Rana P Singh
Girish Sharma
Chapla Agarwal
S Dhanalakshmi
A Ramesha Rao
S Raisuddin
Daniel C F Chan
Anil K Tyagi
Published In
Carcinogenesis
Clin Cancer Res
Breast Cancer Res Treat
Biochem Biophys Res Commun
Affiliations
Soon will be listed here.
Recent Articles
1.
Oral silibinin inhibits lung tumor growth in athymic nude mice and forms a novel chemocombination with doxorubicin targeting nuclear factor kappaB-mediated inducible chemoresistance
Singh R, Mallikarjuna G, Sharma G, Dhanalakshmi S, Tyagi A, Chan D, et al.
Clin Cancer Res . 2004 Dec; 10(24):8641-7. PMID: 15623648
The acute and cumulative dose-related toxicity and drug resistance, mediated via nuclear factor kappaB (NFkappaB), of anthracycline anticancer drugs pose a major problem in cancer chemotherapy. Here, we report that...
2.
Silibinin modulates UVB-induced apoptosis via mitochondrial proteins, caspases activation, and mitogen-activated protein kinase signaling in human epidermoid carcinoma A431 cells
Mohan S, Dhanalakshmi S, Mallikarjuna G, Singh R, Agarwal R
Biochem Biophys Res Commun . 2004 Jun; 320(1):183-9. PMID: 15207719
Several recent studies by us have shown the strong chemopreventive efficacy of silibinin against both ultraviolet B (UVB) radiation and chemical carcinogen-induced tumorigenesis in mouse skin models. The molecular mechanisms...
3.
Silibinin prevents ultraviolet radiation-caused skin damages in SKH-1 hairless mice via a decrease in thymine dimer positive cells and an up-regulation of p53-p21/Cip1 in epidermis
Dhanalakshmi S, Mallikarjuna G, Singh R, Agarwal R
Carcinogenesis . 2004 Mar; 25(8):1459-65. PMID: 15033902
Non-melanoma skin cancer (NMSC) accounts for >1 million new cases each year in the US alone suggesting that more approaches are needed for its prevention and control. Earlier studies by...
4.
In vivo suppression of hormone-refractory prostate cancer growth by inositol hexaphosphate: induction of insulin-like growth factor binding protein-3 and inhibition of vascular endothelial growth factor
Singh R, Sharma G, Mallikarjuna G, Dhanalakshmi S, Agarwal C, Agarwal R
Clin Cancer Res . 2004 Jan; 10(1 Pt 1):244-50. PMID: 14734476
Purpose: Diet composition is an important etiologic factor in prostate cancer (PCA) growth and has significant impact on clinical PCA appearance. Because inositol hexaphosphate (IP6) is a dietary phytochemical present...
5.
Dual efficacy of silibinin in protecting or enhancing ultraviolet B radiation-caused apoptosis in HaCaT human immortalized keratinocytes
Dhanalakshmi S, Mallikarjuna G, Singh R, Agarwal R
Carcinogenesis . 2003 Oct; 25(1):99-106. PMID: 14555614
An increasing incidence of human skin cancer and other adverse effects of solar ultraviolet (UV) radiation enhance the need for novel chemoprevention strategies. Here, we have studied the effect of...
6.
Chemomodulatory influence of Ferula asafoetida on mammary epithelial differentiation, hepatic drug metabolizing enzymes, antioxidant profiles and N-methyl-N-nitrosourea-induced mammary carcinogenesis in rats
Mallikarjuna G, Dhanalakshmi S, Raisuddin S, Rao A
Breast Cancer Res Treat . 2003 Oct; 81(1):1-10. PMID: 14531492
The present study was conducted to ascertain the modulatory influences of Ferula asafoetida L. (asafoetida, flavoring agent) on the mammary epithelial tissue differentiation, hepatic drug metabolizing enzymes, antioxidant profiles and...