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G T Stevenson

Explore the profile of G T Stevenson including associated specialties, affiliations and a list of published articles. Areas
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Articles 102
Citations 653
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Recent Articles
1.
Stevenson G, Anderson V, Leong W
Recent Results Cancer Res . 2002 Jan; 159:104-12. PMID: 11785834
One approach to improving the results of antibody treatment of posttransplant and other lymphomas is to alter the geometry of the antibody molecule so as to enhance its cytotoxicity. When...
2.
Kan K, Anderson V, Leong W, Smith A, Worth A, Stevenson G
J Immunol . 2001 Jan; 166(2):1320-6. PMID: 11145716
We describe a two-stage preparation of chemically engineered Ab constructs, employing as modules Fab'gamma from mAb or rAb, and Fc from human normal IgG1. A multivalent, optionally multispecific F(ab')(n) core...
3.
Stevenson G, Anderson V, Leong W
J Immunol Methods . 2000 Jan; 231(1-2):169-75. PMID: 10648936
We described previously a scheme for linking functionally intact human normal Fcgamma1, via a thioether linkage emerging from its hinge, to any molecule expressing a free sulfhydryl group (SH). The...
4.
Stevenson G, Cragg M
Semin Cancer Biol . 1999 Apr; 9(2):139-47. PMID: 10202135
Molecular mapping of the cell surface has probably proceeded further with the human lymphocyte than with any other mammalian cell, and the B lymphocyte yields a wide range of subtly...
5.
Stevenson G
Lancet . 1999 Feb; 353(9150):340. PMID: 9950433
No abstract available.
6.
Hawkins R, Russell S, Marcus R, Ashworth L, Brissnik J, Zhang J, et al.
Hum Gene Ther . 1997 Jul; 8(10):1287-99. PMID: 9215745
No abstract available.
7.
Stevenson G, Anderson V, Kan K, Worth A
J Immunol . 1997 Mar; 158(5):2242-50. PMID: 9036971
We describe a method for linking human normal Fc gamma1, via stable thioether bonds emerging from its hinge, to any molecule expressing a free sulfhydryl (SH) group. The Fc hinge...
8.
Harris C, Kan K, Stevenson G, Morgan B
Clin Exp Immunol . 1997 Feb; 107(2):364-71. PMID: 9030877
Immunotherapy using MoAbs is inefficient due to limited activation of human effectors by mouse antibodies and multiple protective mechanisms available to host cells against autologous complement. We have used chemically...
9.
Stevenson G
Chem Immunol . 1997 Jan; 65:57-72. PMID: 9018872
No abstract available.
10.
Elsasser D, Valerius T, Repp R, Weiner G, Deo Y, Kalden J, et al.
Blood . 1996 May; 87(9):3803-12. PMID: 8611706
We have investigated the capacity of polymorphonuclear phagocytes (PMN) to lyse malignant B-cell lines using antibodies and antibody derivates to a range of different B-cell antigens. PMN were found to...