G Simms
Overview
Explore the profile of G Simms including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
1876
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Recent Articles
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2.
Rumble B, Retallack R, Hilbich C, Simms G, Multhaup G, Martins R, et al.
N Engl J Med
. 1989 Jun;
320(22):1446-52.
PMID: 2566117
In patients with Alzheimer's disease, amyloid fibrils that are aggregates of A4 protein subunits are deposited in the brain. A similar process occurs at an earlier age in persons with...
3.
Davies L, Wolska B, Hilbich C, Multhaup G, Martins R, Simms G, et al.
Neurology
. 1988 Nov;
38(11):1688-93.
PMID: 3054625
The histologic diagnosis of Alzheimer's disease (AD) might be aided if a more sensitive marker of aberrant A4 amyloid protein deposition were available. We screened a sample of aged brains,...
4.
Guiroy D, Miyazaki M, Multhaup G, Fischer P, Garruto R, Beyreuther K, et al.
Proc Natl Acad Sci U S A
. 1987 Apr;
84(7):2073-7.
PMID: 3470778
The presence of abundant intraneuronal amyloid in the form of neurofibrillary tangles (NFT) in the brains of Guamanian parkinsonism-dementia patients and the absence of extraneuronal amyloid in the form of...
5.
Hartz A, McKinney W, Centor R, Krieg A, Simms G, Henck S
Med Decis Making
. 1986 Jul;
6(3):145-8.
PMID: 3736375
Thresholds have traditionally been represented by a single number; the optimal management of the patient depends on whether his probability of disease is above or below this number. The concept...
6.
Masters C, Multhaup G, Simms G, Pottgiesser J, Martins R, Beyreuther K
EMBO J
. 1985 Nov;
4(11):2757-63.
PMID: 4065091
The protein component of Alzheimer's disease amyloid [neurofibrillary tangles (NFT), amyloid plaque core and congophilic angiopathy] is an aggregated polypeptide with a subunit mass of 4 kd (the A4 monomer)....
7.
Masters C, Simms G, Weinman N, Multhaup G, McDonald B, Beyreuther K
Proc Natl Acad Sci U S A
. 1985 Jun;
82(12):4245-9.
PMID: 3159021
We have purified and characterized the cerebral amyloid protein that forms the plaque core in Alzheimer disease and in aged individuals with Down syndrome. The protein consists of multimeric aggregates...
8.
Williams V, Wetherall J, Simms G, Papadimitriou J
Dev Comp Immunol
. 1981 Jan;
5(4):629-38.
PMID: 7319109
No abstract available.