G Multhaup
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Explore the profile of G Multhaup including associated specialties, affiliations and a list of published articles.
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99
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7268
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Recent Articles
1.
Nowag S, Frangville C, Multhaup G, Marty J, Mingotaud C, Haag R
J Mater Chem B
. 2020 Apr;
2(25):3915-3918.
PMID: 32261642
Core-shell and core-multishell nanocarriers were designed to transport copper ions into cells. Herein, we present their synthesis and physicochemical characterization and demonstrate the high influence of their architectures on the...
2.
Heneka M, Kummer M, Weggen S, Bulic B, Multhaup G, Munter L, et al.
Curr Alzheimer Res
. 2011 Feb;
8(2):115-31.
PMID: 21345168
Alzheimer's disease (AD) is the most common form of neurodegenerative dementias worldwide. Amyloid-β deposition, neurofibrillary tangle formation and Neuroinflammation are the major pathogenetic mechanisms that in concert lead to memory...
3.
Schafer S, Wirths O, Multhaup G, Bayer T
J Neural Transm (Vienna)
. 2006 Nov;
114(3):387-94.
PMID: 17075721
Epidemiological studies have reported a higher prevalence and incidence of Alzheimer's disease (AD) in women. The biochemical basis for this gender-disparate susceptibility is unknown. A gender effect on AD-typical plaque...
4.
Bayer T, Schafer S, Breyhan H, Wirths O, Treiber C, Multhaup G
Clin Neuropathol
. 2006 Jul;
25(4):163-71.
PMID: 16866297
Recent evidence indicates that both intraneuronal Abeta and Cu are involved in the pathological processes in Alzheimer's disease (AD). This perspective shows a possible interrelation of these factors. AbetaPP, the...
5.
Kessler H, Pajonk F, Meisser P, Schneider-Axmann T, Hoffmann K, Supprian T, et al.
J Neural Transm (Vienna)
. 2006 Jun;
113(11):1763-9.
PMID: 16736242
Increasing evidence links Alzheimer's disease (AD) with misbalanced Cu homeostasis. Recently, we have shown that dietary Cu supplementation in a transgenic mouse model for AD increases bioavailable brain Cu levels,...
6.
Kessler H, Pajonk F, Supprian T, Falkai P, Multhaup G, Bayer T
Nervenarzt
. 2005 May;
76(5):581-5.
PMID: 15905983
Alzheimer's dementia (AD) is a chronically progressive neurodegenerative disease. The key protein in the pathophysiology of AD is the amyloid precursor protein (APP) which releases the amyloid-beta peptide (Abeta) by...
7.
Fassbender K, Walter S, Kuhl S, Landmann R, Ishii K, Bertsch T, et al.
FASEB J
. 2003 Nov;
18(1):203-5.
PMID: 14597556
To rapidly respond to invading microorganisms, humans call on their innate immune system. This occurs by microbe-detecting receptors, such as CD14, that activate immune cells to eliminate the pathogens. Here,...
8.
Schumann K, Classen H, Dieter H, Konig J, Multhaup G, Rukgauer M, et al.
Eur J Clin Nutr
. 2002 May;
56(6):469-83.
PMID: 12032645
Copper (Cu) is an essential trace element with many physiological functions. Homeostatic mechanisms exist to allow Cu to act as a cofactor in enzymatic processes and to prevent accumulation of...
9.
Wirths O, Multhaup G, Czech C, Blanchard V, Tremp G, Pradier L, et al.
Neurosci Lett
. 2001 Dec;
316(3):145-8.
PMID: 11744223
There is circumstantial evidence that the reelin signaling pathway may contribute to neurodegeneration in the adult brain and could be linked to Alzheimer's disease (AD). In the present immunohistochemical report...
10.
Multhaup G, Strausak D, Bissig K, Solioz M
Biochem Biophys Res Commun
. 2001 Oct;
288(1):172-7.
PMID: 11594769
Intracellular copper routing in Enterococcus hirae can be accomplished by the CopZ metallochaperone. Using surface plasmon resonance analysis, we show here that CopZ interacts with the CopA copper ATPase. The...