G S Yochum
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Explore the profile of G S Yochum including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
322
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0
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Recent Articles
1.
Schieffer K, Williams E, Yochum G, Koltun W
Aliment Pharmacol Ther
. 2016 Aug;
44(8):817-35.
PMID: 27554912
Background: A total proctocolectomy followed by ileal pouch-anal anastomosis is a potentially curative surgery for ulcerative colitis or familial adenomatous polyposis. About 5-35% of patients with ulcerative colitis and 0-11%...
2.
Yochum G, Ayer D
Mol Cell Biol
. 2001 Jun;
21(13):4110-8.
PMID: 11390640
The mSin3A-histone deacetylase corepressor is a multiprotein complex that is recruited by DNA binding transcriptional repressors. Sin3 has four paired amphipathic alpha helices (PAH1 to -4) that are protein-protein interaction...
3.
Brubaker K, Cowley S, Huang K, Loo L, Yochum G, Ayer D, et al.
Cell
. 2000 Dec;
103(4):655-65.
PMID: 11106735
Gene-specific targeting of the Sin3 corepressor complex by DNA-bound repressors is an important mechanism of gene silencing in eukaryotes. The Sin3 corepressor specifically associates with a diverse group of transcriptional...
4.
Adler A, Huang C, Yochum G, Marsh D, Pardoll D
J Immunol
. 2000 Jan;
164(2):649-55.
PMID: 10623806
In vitro studies have suggested that tolerance induction (i.e., anergy) is associated with an inability of T cells to proliferate vigorously upon Ag recognition. In vivo, the relationship between T...
5.
Laherty C, Billin A, Lavinsky R, Yochum G, Bush A, Sun J, et al.
Mol Cell
. 1998 Aug;
2(1):33-42.
PMID: 9702189
The transcriptional corepressor mSin3 is found in a large multiprotein complex containing the histone deacetylases HDAC1 and HDAC2, in addition to at least five tightly associated polypeptides. We have cloned...
6.
Adler A, Marsh D, Yochum G, Guzzo J, Nigam A, Nelson W, et al.
J Exp Med
. 1998 Jun;
187(10):1555-64.
PMID: 9584134
T cell tolerance to parenchymal self-antigens is thought to be induced by encounter of the T cell with its cognate peptide-major histocompatibility complex (MHC) ligand expressed on the parenchymal cell,...