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G R Tintinger

Explore the profile of G R Tintinger including associated specialties, affiliations and a list of published articles. Areas
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Articles 18
Citations 161
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Recent Articles
11.
Gravett C, Theron A, Steel H, Tintinger G, Cockeran R, Feldman C, et al.
Eur Respir J . 2010 Apr; 36(6):1417-24. PMID: 20413544
The research question addressed in the current study was: do formoterol (1 and 10 nM) and montelukast (2 μM) possess interactive inhibitory effects on activated human neutrophils, particularly in relation...
12.
Steel H, Theron A, Tintinger G, Anderson R
J Antimicrob Chemother . 2009 Sep; 64(5):1008-12. PMID: 19744985
Objectives: This study was designed to investigate the neutrophil-targeted anti-inflammatory potential of posaconazole (0.1-5 microM, equivalent to 0.7-3.9 mg/L) by measuring the effects of this agent on the release of...
13.
Theron A, Gravett C, Steel H, Tintinger G, Feldman C, Anderson R
Inflamm Res . 2009 Feb; 58(5):263-8. PMID: 19184354
Objective And Design: To investigate the sensitizing effects of the cysteinyl leukotrienes (CysLTs) C(4) and D(4) on the proinflammatory responses of chemoattractant-activated human neutrophils in vitro. Materials: Neutrophils were isolated...
14.
Steel H, Tintinger G, Theron A, Anderson R
Clin Exp Immunol . 2007 Aug; 150(1):144-50. PMID: 17683509
The primary objective of this study was to probe the involvement of leukotriene B(4) (LTB(4)) in itraconazole (0.1-5 microM)-mediated inhibition of Ca(2+) uptake by chemoattractant-activated human neutrophils. Following exposure of...
15.
Tintinger G, Anderson R, Ker J
S Afr Med J . 2003 Feb; 92(12):990-6. PMID: 12561417
Objectives: The objectives of the current study were to: (i) present an integrated model for the restoration of calcium homeostasis in activated human neutrophils based on current knowledge and recent...
16.
Theron A, Steel H, Tintinger G, Anderson R
Inflamm Res . 2003 Feb; 51(12):594-602. PMID: 12558193
Objective And Design: To identify the involvement of adenosine in restoration of Ca2+ homeostasis to activated human neutrophils. Materials: Neutrophils were isolated from venous blood taken from healthy, adult, human...
17.
Tintinger G, Theron A, Anderson R, Ker J
Biochem Pharmacol . 2001 Apr; 61(10):1319-28. PMID: 11322936
This study was designed to evaluate the effects of epinephrine (0.01-1 microM) on superoxide production by, and release of elastase from human neutrophils activated with the chemotactic tripeptide, N-formyl-L-methionyl-L-leucyl-L-phenylalanine (FMLP)...
18.
Tintinger G, Theron A, Steel H, Anderson R
Clin Exp Immunol . 2001 Feb; 123(2):254-63. PMID: 11207656
The relationship between activation of NADPH-oxidase, alterations in membrane potential and triggering of Ca2+ fluxes in human phagocytes has been investigated using neutrophils from four subjects with chronic granulomatous disease...