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G Pompucci

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Articles 51
Citations 94
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Recent Articles
1.
Vettori A, Pompucci G, Paolini B, Del Ciondolo I, Bressan S, Dundar M, et al.
Eur Rev Med Pharmacol Sci . 2019 Mar; 23(4):1751-1761. PMID: 30840300
Objective: To summarize the latest information on the relationship between genes and common forms of obesity, and to review genetic markers (SNPs and miRNA) that play a role in predisposing...
2.
Paolini B, Maltese P, Del Ciondolo I, Tavian D, Missaglia S, Ciuoli C, et al.
Genet Mol Res . 2016 Oct; 15(3). PMID: 27706562
Obesity is a major public health concern; despite evidence of high heritability, the genetic causes of obesity remain unclear. In this study, we assessed the presence of mutations in three...
3.
Cerboni B, Di Stefano A, Micheli V, Morozzi G, Pompucci G, Sestini S
Nucleosides Nucleotides Nucleic Acids . 2010 Jun; 29(4-6):471-5. PMID: 20544540
The enzyme poly(ADP-ribose) polymerase (PARP-1, EC 2.4.2.30) is activated by DNA strand breaks caused by several agents and utilizes NAD to form polyADPR, bound to acceptor proteins. The involvement of...
4.
Micheli V, Jacomelli G, Sestini S, Notarantonio L, Cerboni B, Peruzzi L, et al.
Nucleosides Nucleotides Nucleic Acids . 2004 Dec; 23(8-9):1189-91. PMID: 15571228
Aim of this study was to ascertain whether allopurinol, usually administered to hypoxanthine-guanine phosphoribosyltransferase (HPRT) deficient patients, or metabolites abnormally increased in HPRT deficient erythrocytes (NAD, PPribP) could be directly...
5.
Aleo M, Giudici M, Sestini S, Danesi P, Pompucci G, Preti A
J Cell Biochem . 2001 Jan; 80(3):360-6. PMID: 11135366
Extracellular NAD is degraded to pyridine and purine metabolites by different types of surface-located enzymes which are expressed differently on the plasmamembrane of various human cells and tissues. In a...
6.
Sestini S, Jacomelli G, Pescaglini M, Micheli V, Pompucci G
Arch Biochem Biophys . 2000 Jul; 379(2):277-82. PMID: 10898945
Pyridine nucleotide levels and the activities of enzymes involved in NAD synthesis (nicotinic acid phosphoribosyltransferase, nicotinic acid- and nicotinamide mononucleotide-adenylyltransferase) have been assayed in human normal lymphocytes by an HPLC...
7.
Micheli V, Sestini S, Rocchigiani M, Jacomelli G, Manzoni F, Peruzzi L, et al.
Life Sci . 1999 Jul; 64(26):2479-87. PMID: 10403507
Purine and pyridine metabolism were studied in ten Lesch-Nyhan patients, with virtually no hypoxanthine-guanine phosphoribosyltransferase (HPRT) activity in erythrocytes. Increased NAD erythrocyte concentrations were found in all patients. Raised activities...
8.
Sestini S, Micheli V, Rocchigiani M, Jacomelli G, Manzoni F, Gathof B, et al.
Adv Exp Med Biol . 1998 May; 431:181-4. PMID: 9598055
No abstract available.
9.
Micheli V, Jacomelli G, Zammarchi E, Pompucci G
Adv Exp Med Biol . 1998 May; 431:161-5. PMID: 9598051
No abstract available.
10.
Micheli V, Jacomelli G, Fioravanti A, Morozzi G, Marcolongo R, Pompucci G
Clin Chim Acta . 1997 Mar; 259(1-2):161-8. PMID: 9086303
A non-radioactive method that uses reverse-phase high performance liquid chromatography is described for the determination of thiopurine methyltransferase (E.C. 2.1.1.67) activity in human erythrocytes. The method is based on the...