G N Pavlakis
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Explore the profile of G N Pavlakis including associated specialties, affiliations and a list of published articles.
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92
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4407
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Recent Articles
1.
Thaysen-Andersen M, Chertova E, Bergamaschi C, Moh E, Chertov O, Roser J, et al.
Glycoconj J
. 2015 Nov;
33(3):417-33.
PMID: 26563299
Human interleukin 15 (IL-15) circulates in blood as a stable molecular complex with the soluble IL-15 receptor alpha (sIL-15Rα). This heterodimeric IL-15:sIL-15Rα complex (hetIL-15) shows therapeutic potential by promoting the...
2.
Bergamaschi C, Kulkarni V, Rosati M, Alicea C, Jalah R, Chen S, et al.
Gene Ther
. 2014 Oct;
22(1):76-86.
PMID: 25273353
Interleukin-15 (IL-15) is a common γ-chain cytokine that has a significant role in the activation and proliferation of T and NK cells and holds great potential in fighting infection and...
3.
Vaccari M, Boasso A, Ma Z, Cecchinato V, Venzon D, Doster M, et al.
Mucosal Immunol
. 2008 Dec;
1(6):497-507.
PMID: 19079217
Systemic immunization of macaques with a combination of DNA-poxvirus-based vaccines confers protection from high level of both systemic and mucosal viral replication following rectal exposure to the pathogenic SIV(mac251). Here...
4.
Robinson T, Sidhu M, Pavlakis G, Felber B, Silvera P, Lewis M, et al.
J Med Primatol
. 2007 Aug;
36(4-5):276-84.
PMID: 17669216
Background: The cell mediated immune profiles following immunization with a recombinant DNA vaccine was assessed in the simian-human immunodeficiency virus (SHIV) and Macaque model. Earlier work demonstrated increased numbers of...
5.
Hel Z, Tsai W, Thornton A, Nacsa J, Giuliani L, Tryniszewska E, et al.
J Immunol
. 2001 Dec;
167(12):7180-91.
PMID: 11739541
T cell-mediated immune responses play an important role in the containment of HIV-1 replication. Therefore, an effective vaccine against HIV-1 should be able to elicit high frequencies of virus-specific CD8(+)...
6.
Kino T, Stauber R, Resau J, Pavlakis G, Chrousos G
J Clin Endocrinol Metab
. 2001 Nov;
86(11):5600-8.
PMID: 11701741
The syndrome of familial or sporadic glucocorticoid resistance is characterized by hypercortisolism without the clinical stigmata of Cushing syndrome. This condition is usually caused by mutations of the human GR,...
7.
Rosati M, Valentin A, Patenaude D, Pavlakis G
J Immunol
. 2001 Jul;
167(3):1654-62.
PMID: 11466389
C/EBPbeta is a member of a family of leucine zipper transcription factors that are involved in regulating the expression of several cytokines, including IL-1, IL-6, IL-8, TNF, and macrophage-inflammatory protein-1alpha....
8.
Nappi F, Schneider R, Zolotukhin A, Smulevitch S, Michalowski D, Bear J, et al.
J Virol
. 2001 Apr;
75(10):4558-69.
PMID: 11312326
Human immunodeficiency virus (HIV) and all other lentiviruses utilize the essential viral protein Rev, which binds to RRE RNA, to export their unspliced and partially spliced mRNAs from the nucleus....
9.
Neumann M, Afonina E, Ceccherini-Silberstein F, Schlicht S, Erfle V, Pavlakis G, et al.
J Cell Sci
. 2001 Apr;
114(Pt 9):1717-29.
PMID: 11309202
Astrocytes are cellular targets for the human immunodeficiency virus (HIV) that limit virus production, owing, at least in part, to the diminished functionality of the viral post-transcriptional stimulatory factor Rev....
10.
Valentin A, Trivedi H, Lu W, Kostrikis L, Pavlakis G
Virology
. 2001 Feb;
269(2):294-304.
PMID: 10753708
CCR5 and CXCR4 are the main coreceptors for non-syncytia-inducing (NSI) and syncytia-inducing (SI) HIV-1 strains, respectively. NSI HIV-1 isolates do not infect either human lymphoid or monocytoid cell lines, and...