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G Locke

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Citations 32
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Recent Articles
1.
Sanmamed N, Locke G, Crook J, Liu A, Raman S, Glicksman R, et al.
Clin Oncol (R Coll Radiol) . 2023 Feb; 35(4):262-268. PMID: 36737311
Aims: To report long-term oncological outcomes of men treated prospectively as part of the American College of Surgeons Oncology Group phase III Surgical Prostatectomy Versus Interstitial Radiation Intervention Trial (SPIRIT)...
2.
Ong L, Vasta J, Monereau L, Locke G, Ribeiro H, Pattoli M, et al.
SLAS Discov . 2019 Nov; 25(2):176-185. PMID: 31709883
Protein kinases are intensely studied mediators of cellular signaling. While traditional biochemical screens are capable of identifying compounds that modulate kinase activity, these assays are limited in their capability of...
3.
Fiorentini G, Schmitz D, Rodrigues P, Aliaga L, Altinok O, Baldin B, et al.
Phys Rev Lett . 2013 Jul; 111(2):022502. PMID: 23889389
We report a study of ν(μ) charged-current quasielastic events in the segmented scintillator inner tracker of the MINERvA experiment running in the NuMI neutrino beam at Fermilab. The events were...
4.
Fields L, Chvojka J, Aliaga L, Altinok O, Baldin B, Baumbaugh A, et al.
Phys Rev Lett . 2013 Jul; 111(2):022501. PMID: 23889388
We have isolated ν(μ) charged-current quasielastic (QE) interactions occurring in the segmented scintillator tracking region of the MINERvA detector running in the NuMI neutrino beam at Fermilab. We measure the...
5.
Marcinkeviciene J, Jiang W, Kopcho L, Locke G, Luo Y, Copeland R
Arch Biochem Biophys . 2001 May; 390(1):101-8. PMID: 11368521
Steady-state kinetics, equilibrium binding, and primary substrate kinetic isotope effect studies revealed that the reduction of crotonyl-CoA by NADH, catalyzed by Haemophilus influenzae enoyl-ACP reductase (FabI), follows a rapid equilibrium...
6.
Jiang W, Locke G, Harpel M, Copeland R, Marcinkeviciene J
Biochemistry . 2000 Jul; 39(27):7990-7. PMID: 10891080
Chemical modification, mutagenesis, chemical rescue, and isotope effect studies are used to identify and probe the roles of several conserved amino acid groups in catalysis by human dihydroorotate dehydrogenase. Time-...
7.
Marcinkeviciene J, Jiang W, Locke G, Kopcho L, Rogers M, Copeland R
Arch Biochem Biophys . 2000 Apr; 377(1):178-86. PMID: 10775458
We report the identification, expression, and characterization of a second Dihydroorotate dehydrogenase (DHODase A) from the human pathogen Enterococcus faecalis. The enzyme consists of a polypeptide chain of 322 amino...
8.
Locke G
Nurs Stand . 1993 Aug; 7(48):25-9. PMID: 8398762
Staff working with patients with burns are regularly exposed to large amounts of potentially infected blood. With the steady rise of HIV infection in the general population it is no...
9.
Locke G
Nurs Stand . 1992 Oct; 7(3):25-7. PMID: 1449992
A patient with major burns requires intervention from highly skilled nursing and medical teams on arrival at the accident and emergency department, and those staff without proper training can lack...
10.
Locke G, Gazzard A
Nurs Stand . 1991 Feb; 5(21):48-50. PMID: 1900175
No abstract available.