G L Warnock
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Explore the profile of G L Warnock including associated specialties, affiliations and a list of published articles.
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140
Citations
2982
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Recent Articles
11.
Law E, Lu S, Kieffer T, Warnock G, Ao Z, Woo M, et al.
Diabetologia
. 2010 Apr;
53(7):1415-27.
PMID: 20369225
Aims/hypothesis: Type 2 diabetes is characterised by decreased beta cell mass and islet amyloid formation. Islet amyloid formed by aggregation of human islet amyloid polypeptide (hIAPP) is associated with beta...
12.
Potter K, Abedini A, Marek P, Klimek A, Butterworth S, Driscoll M, et al.
Proc Natl Acad Sci U S A
. 2010 Feb;
107(9):4305-10.
PMID: 20160085
Islet transplantation is a promising treatment for diabetes but long-term success is limited by progressive graft loss. Aggregates of the beta cell peptide islet amyloid polypeptide (IAPP) promote beta cell...
13.
Klimek A, Soukhatcheva G, Thompson D, Warnock G, Salehi M, Rilo H, et al.
Am J Transplant
. 2009 Aug;
9(9):2119-25.
PMID: 19706025
We sought to determine whether recipients of islet transplants have defective proinsulin processing. Individuals who had islet allo- or autotransplantation were compared to healthy nondiabetic subjects. Insulin (I), total proinsulin...
14.
Tashiro H, Iwata H, Warnock G, Tanigawa M, Ototani Y, Tsuji T
Transplant Proc
. 2005 Nov;
37(8):3512-3.
PMID: 16298645
We evaluated the functional efficacy of microencapsulated porcine islet xenografts transplanted into nonobese diabetic (NOD) mice. Islets were isolated from the pancreata of CSK miniature swine by manual collagenase digestion...
15.
16.
Lakey J, Helms L, Kin T, Korbutt G, Rajotte R, Shapiro A, et al.
Transplantation
. 2001 Sep;
72(4):565-70.
PMID: 11544413
Background: Islet isolation from the pancreatic tissue matrix remains highly variable. Recent evidence suggests that intrinsic human pancreatic proteases, including trypsin, may inhibit effective collagenase enzymatic activity during islet isolation,...
17.
Shapiro J, Ryan E, Warnock G, Kneteman N, Lakey J, Korbutt G, et al.
BMJ
. 2001 Apr;
322(7290):861.
PMID: 11290632
No abstract available.
18.
Ryan E, Lakey J, Rajotte R, Korbutt G, Kin T, Imes S, et al.
Diabetes
. 2001 Apr;
50(4):710-9.
PMID: 11289033
Islet transplantation offers the prospect of good glycemic control without major surgical risks. After our initial report of successful islet transplantation, we now provide further data on 12 type 1...
19.
Shapiro A, Lakey J, Ryan E, Korbutt G, Toth E, Warnock G, et al.
N Engl J Med
. 2000 Jul;
343(4):230-8.
PMID: 10911004
Background: Registry data on patients with type 1 diabetes mellitus who undergo pancreatic islet transplantation indicate that only 8 percent are free of the need for insulin therapy at one...
20.
Warnock G
Can J Surg
. 1999 Dec;
42(6):421-6.
PMID: 10593242
Transplantation of insulin-secreting tissue represents a physiologic approach to reverse diabetes mellitus. Pancreas transplants yield a remarkable enhancement in quality of life and appear to modify the devastating neurovascular complications...