G J Self
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Explore the profile of G J Self including associated specialties, affiliations and a list of published articles.
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10
Citations
74
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Recent Articles
1.
Hay D, Douglas S, Ao Z, Moesker R, Self G, Rigby P, et al.
Br J Pharmacol
. 2001 Apr;
132(8):1905-15.
PMID: 11309263
The role of endothelin B (ET(B)) receptors in mediating ET ligand-induced contractions in mouse trachea was examined in ET(B) receptor knockout animals. Autoradiographic binding studies, using [(125)I]-ET-1, confirmed the presence...
2.
Goldie R, DAprile A, Self G, Rigby P, Henry P
J Cardiovasc Pharmacol
. 2000 Nov;
36(5 Suppl 1):S228-31.
PMID: 11078384
Endothelin-1(1-21) (ET-1(1-21)) is a strong candidate as a significant mediator in asthma, in part because of its powerful spasmogenic actions and its ability to enhance cholinergic nerve-mediated contraction in human...
3.
Goldie R, DAprile A, Self G, Rigby P, Henry P
Br J Pharmacol
. 1996 Feb;
117(4):729-35.
PMID: 8646421
1. Quantitative autoradiographic studies were conducted to determine the distributions and densities of endothelin-A (ETA) and ETB receptor subtypes in peripheral lung alveolar wall tissue of the rat, guinea-pig and...
4.
Goldie R, Henry P, Knott P, Self G, Luttmann M, Hay D
Am J Respir Crit Care Med
. 1995 Nov;
152(5 Pt 1):1653-8.
PMID: 7582310
The potent bronchoconstrictor and mitogenic actions of the peptide endothelin-1 (ET-1) on airway smooth muscle may contribute significantly to the bronchial obstruction observed in asthma. However, the status of the...
5.
Goldie R, Grayson P, Knott P, Self G, Henry P
Br J Pharmacol
. 1994 Jul;
112(3):749-56.
PMID: 7921598
1. Autoradiographic studies were conducted to investigate the receptor subtypes for endothelin-1 (ET-1) that were present in the ovine respiratory tract. In addition, the receptor subtypes mediating contraction of airway...
6.
Rigby P, Self G, Goldie R
Eur J Pharmacol
. 1992 Sep;
228(2-3):141-5.
PMID: 1446718
The present study further characterizes ascorbic acid-dependent 125I- ion binding in guinea-pig trachea. Binding of 125I- ion in the presence of ascorbic acid was detected at the epithelial/submucosal interface, apparently...
7.
Henry P, Rigby P, Self G, Preuss J, Goldie R
Br J Pharmacol
. 1992 Jan;
105(1):135-41.
PMID: 1596675
1. The effects of endothelin-1 (ET-1) and of the muscarinic cholinoceptor agonist, carbachol, on [3H]-inositol phosphate ([3H]-InsP) accumulation and smooth muscle contraction were determined in rat isolated tracheal tissue. 2....
8.
Henry P, Rigby P, Self G, Preuss J, Goldie R
Br J Pharmacol
. 1990 Aug;
100(4):786-92.
PMID: 2169940
1. Endothelin-1 (ET-1) binding site densities and constrictor activities were compared in airway smooth muscle preparations of human, guinea-pig, rat and mouse. 2. The mean contractile response to 0.3 microM...
9.
Self G, Rigby P, Passarelli M, Goldie R
Eur J Pharmacol
. 1990 Feb;
176(2):169-76.
PMID: 2311664
We have examined some of the binding characteristics and the autoradiographic distribution of binding sites for Na125I (I-Na) in airway tissue from the guinea-pig, monkey, pig, rat, mouse and from...
10.
Rigby P, Passarelli M, Self G, Preuss J, Goldie R
Biochem Pharmacol
. 1988 Apr;
37(7):1421-4.
PMID: 2833281
No abstract available.