G J Lieschke
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Explore the profile of G J Lieschke including associated specialties, affiliations and a list of published articles.
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45
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1490
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Recent Articles
1.
Keightley M, Markmiller S, Love C, Rasko J, Lieschke G, Heath J
Methods Cell Biol
. 2016 Jul;
135:259-88.
PMID: 27443930
From a fixed number of genes carried in all cells, organisms create considerable diversity in cellular phenotype through differential regulation of gene expression. One prevalent source of transcriptome diversity is...
2.
Wittmann C, Chockley P, Singh S, Pase L, Lieschke G, Grabher C
Adv Hematol
. 2012 Jun;
2012:541471.
PMID: 22737171
Starting as a model for developmental genetics, embryology, and organogenesis, the zebrafish has become increasingly popular as a model organism for numerous areas of biology and biomedicine over the last...
3.
Lieschke G, Oates A, Crowhurst M, Ward A, Layton J
Blood
. 2001 Nov;
98(10):3087-96.
PMID: 11698295
The zebrafish is a useful model organism for developmental and genetic studies. The morphology and function of zebrafish myeloid cells were characterized. Adult zebrafish contain 2 distinct granulocytes, a heterophil...
4.
5.
Lieschke G
Int J Hematol
. 2001 May;
73(1):23-31.
PMID: 11372751
Now that whole genomes are sequenced, the identification of gene function rather than gene discovery is a major challenge. Saturation mutagenesis and screening for mutant phenotypes are methods that allow...
6.
Sun X, Layton J, Elefanty A, Lieschke G
Blood
. 2001 Mar;
97(7):2008-15.
PMID: 11264165
STI571 (formerly CGP57148) and AG957 are small molecule inhibitors of the protein tyrosine kinase (PTK) p145(abl) and its oncogenic derivative p210(bcr-abl). AG490 is an inhibitor of the PTK Janus kinase...
7.
Mannering S, Zhan Y, Gilbertson B, Lieschke G, Cheers C
Immunology
. 2000 Sep;
101(1):132-9.
PMID: 11012764
Little is known about the role of granulocyte colony-stimulating factor (G-CSF) in the response to chronic bacterial infections. To address this we infected G-CSF knock out (G-CSF-/-) mice with Mycobacterium...
8.
Zhan Y, Basu S, Lieschke G, Grail D, Dunn A, Cheers C
J Leukoc Biol
. 1999 Mar;
65(2):256-64.
PMID: 10088609
Gene-targeted mice lacking the hemopoietic growth factors, granulocyte colony-stimulating factor (G-CSF) or granulocyte-macrophage (GM)-CSF, show increased susceptibility to infection with the facultative intracellular bacterium, Listeria monocytogenes. The resident peritoneal cell...
9.
Zhan Y, Lieschke G, Grail D, Dunn A, Cheers C
Blood
. 1998 Feb;
91(3):863-9.
PMID: 9446646
The in vivo roles of granulocyte-macrophage colony-stimulating factor (GM-CSF) and granulocyte (G)-CSF were studied in factor-deficient gene-targeted knockout mice infected with the facultative intracellular bacterium Listeria monocytogenes. Previous results showed...
10.
Seymour J, Lieschke G, Grail D, Quilici C, Hodgson G, Dunn A
Blood
. 1997 Oct;
90(8):3037-49.
PMID: 9376584
Mice lacking granulocyte colony-stimulating factor (G-CSF) are neutropenic with reduced hematopoietic progenitors in the bone marrow and spleen, whereas those lacking granulocyte-macrophage colony-stimulating factor (GM-CSF) have impaired pulmonary homeostasis and...