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G J Lieschke

Explore the profile of G J Lieschke including associated specialties, affiliations and a list of published articles. Areas
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Articles 45
Citations 1490
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11.
Basu S, Dunn A, Marino M, Savoia H, Hodgson G, Lieschke G, et al.
J Immunol . 1997 Aug; 159(3):1412-7. PMID: 9233638
The contribution of granulocyte-macrophage CSF (GM-CSF) to endotoxin-mediated septic shock has been assessed by treating GM-CSF-deficient mice with LPS. Hypothermia and loss in body weight were markedly attenuated in LPS-treated...
12.
Lieschke G, Foote M, Morstyn G
Cancer Chemother Biol Response Modif . 1997 Jan; 17:363-89. PMID: 9551221
No abstract available.
13.
Lieschke G
Ciba Found Symp . 1997 Jan; 204:60-74; discussion 74-7. PMID: 9107411
Haemopoietic growth factor-deficient mice have been particularly instructive for defining the usual physiological role of these factors. Mice now exist lacking the granulopoietic factors G-CSF, GM-CSF, M-CSF (CSF-1), SCF, several...
14.
Lieschke G, Rao P, Gately M, Mulligan R
Nat Biotechnol . 1997 Jan; 15(1):35-40. PMID: 9035103
Interleukin-12 (IL-12) is unique amongst cytokines in being a disulfide-linked heterodimer of two separately encoded subunits (p35 and p40). We expressed single chain IL-12 proteins from retroviral constructs in which...
15.
Vremec D, Lieschke G, Dunn A, Robb L, Metcalf D, Shortman K
Eur J Immunol . 1997 Jan; 27(1):40-4. PMID: 9021996
To ascertain whether the development of dendritic cells (DC) in mouse lymphoid organs is dependent on granulocyte/macrophage colony-stimulating factor (GM-CSF), we determined the number of DC in the thymus, spleen...
16.
Morstyn G, Foote M, Lieschke G
Cancer Chemother Biol Response Modif . 1996 Jan; 16:295-314. PMID: 8639388
No abstract available.
17.
Nilsson S, Lieschke G, Williams B, Tzelepis D, Hodgson G, Grail D, et al.
Blood . 1995 Jul; 86(1):66-72. PMID: 7795257
Osteopetrotic (op/op) mice are characterized by an autosomal recessive inactivating mutation resulting in the absence of biologically active colony-stimulating factor-1 (CSF-1). Consequently, young op/op mice have a severe deficiency of...
18.
Cincotta R, Balloch A, Metz J, Layton J, Lieschke G
Am J Hematol . 1995 Apr; 48(4):288. PMID: 7536392
No abstract available.
19.
Lieschke G, Dunn A
Exp Hematol . 1995 Apr; 23(4):328-34. PMID: 7534713
When cultured under appropriate in vitro conditions, embryonal stem cells (ESCs) form embryoid bodies (EBs) that contain mature hematopoietic cells, including cells of the monocyte-macrophage lineage. A two-step in vitro...
20.
Maher D, Lieschke G, Green M, Bishop J, Stuart-Harris R, Wolf M, et al.
Ann Intern Med . 1994 Oct; 121(7):492-501. PMID: 7520676
Objective: To determine if filgrastim (recombinant human methionyl granulocyte colony-stimulating factor) used in addition to standard inpatient antibiotic therapy accelerated recovery from infection associated with chemotherapy-induced neutropenia. Design: Randomized, double-blind,...