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G H Williams

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Articles 394
Citations 4436
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Recent Articles
1.
Baudrand R, Lian C, Lian B, Ricchiuti V, Yao T, Li J, et al.
Nutr Metab Cardiovasc Dis . 2014 Jan; 24(1):34-41. PMID: 24418377
Background/aim: Obesity is associated with changes in adiponectin and pro-inflammatory adipokines. Sodium intake can affect adipokine secretion suggesting a role in cardiovascular dysfunction. We tested if long-term dietary sodium restriction...
2.
Saxena A, Chamarthi B, Williams G, Hopkins P, Seely E
J Hum Hypertens . 2013 Nov; 28(5):292-7. PMID: 24226101
Age, sex, hypertension and dietary sodium are proposed to affect plasma and urinary catecholamines. Yet no prior study has examined the simultaneous effects of these factors within the same study...
3.
Garg R, Kneen L, Williams G, Adler G
Diabetes Obes Metab . 2013 Oct; 16(3):268-72. PMID: 24125483
Aim: Obese individuals have high aldosterone levels that may contribute to insulin resistance (IR) and endothelial dysfunction leading to obesity-induced cardiovascular disease. We conducted a study to evaluate the effect...
4.
Dudderidge T, Kelly J, Wollenschlaeger A, Okoturo O, Prevost T, Robson W, et al.
Br J Cancer . 2010 Jul; 103(5):701-7. PMID: 20648010
Background: The accuracy of prostate-specific antigen (PSA) testing in prostate cancer detection is constrained by low sensitivity and specificity. Dysregulated expression of minichromosome maintenance (Mcm) 2-7 proteins is an early...
5.
Loddo M, Kingsbury S, Rashid M, Proctor I, Holt C, Young J, et al.
Br J Cancer . 2009 Feb; 100(6):959-70. PMID: 19240714
Multiparameter analysis of core regulatory proteins involved in G1-S and G2-M cell-cycle transitions provides a powerful biomarker readout for assessment of the cell-cycle state. We have applied this algorithm to...
6.
Harrington B, Smith K, Hunter D, Marks L, Blackman T, McKee L, et al.
Public Health . 2008 Dec; 123(1):e24-8. PMID: 19084881
Objectives: The election of a Labour government in 1997 brought the issue of health inequalities firmly back on to the policy agenda across the UK. Since then, in the wake...
7.
Simpson J, Ince P, Higham C, Gelsthorpe C, Fernando M, Matthews F, et al.
Neuropathol Appl Neurobiol . 2007 Nov; 33(6):670-83. PMID: 17990995
White matter lesions (WML), a common feature in brain ageing, are classified as periventricular (PVL) or deep subcortical (DSCL), depending on their anatomical location. Microglial activation is implicated in a...
8.
Dudderidge T, McCracken S, Loddo M, Fanshawe T, Kelly J, Neal D, et al.
Br J Cancer . 2007 Apr; 96(9):1384-93. PMID: 17406359
Activation of mitogen/extracellular-signal-regulated kinase kinase 5/extracellular signal-regulated kinase-5 (MEK5/ERK5) growth signalling is coupled to increased cell proliferation in prostate cancer (PCa). Dysregulation of the DNA replication licensing pathway, a critical...
9.
Wharton S, Maltby E, Jellinek D, Levy D, Atkey N, Hibberd S, et al.
Acta Neuropathol . 2006 Dec; 113(2):119-27. PMID: 17160531
Oligodendrogliomas may be divided into those with deletion of chromosomes 1p and 19q (Del+), and those without (Del-). Del+ tumours show better survival and chemoresponsiveness but the reason for this...
10.
Williams J, Williams G, Raji A, Jeunemaitre X, Brown N, Hopkins P, et al.
J Hum Hypertens . 2005 Nov; 20(2):129-36. PMID: 16292348
Screening for primary hyperaldosteronism (PHA) is often indicated in individuals with resistant hypertension or hypokalaemia. However, in the far larger subset of the hypertensive population who do not fit into...