G E Landreth
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Explore the profile of G E Landreth including associated specialties, affiliations and a list of published articles.
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54
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2099
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Recent Articles
11.
Selcher J, Nekrasova T, Paylor R, Landreth G, Sweatt J
Learn Mem
. 2001 Feb;
8(1):11-9.
PMID: 11160759
The extracellular signal-regulated kinases (ERKs) are members of the mitogen-activated protein kinase (MAPK) superfamily of enzymes and have recently garnered considerable attention in the field of learning and memory. ERK...
12.
Combs C, Karlo J, Kao S, Landreth G
J Neurosci
. 2001 Feb;
21(4):1179-88.
PMID: 11160388
Reactive microglia associated with the beta-amyloid plaques in Alzheimer's disease (AD) brains initiate a sequence of inflammatory events integral to the disease process. We have observed that fibrillar beta-amyloid peptides...
13.
Menegay H, Myers M, Moeslein F, Landreth G
J Cell Sci
. 2000 Aug;
113 ( Pt 18):3241-53.
PMID: 10954422
CLK1 was one of the first identified dual specificity kinases and is the founding member of the 'LAMMER' family of kinases. We have established the substrate site specificity of CLK1....
14.
Combs C, Johnson D, Karlo J, Cannady S, Landreth G
J Neurosci
. 2000 Jan;
20(2):558-67.
PMID: 10632585
Alzheimer's disease (AD) is characterized by the extracellular deposition of beta-amyloid fibrils within the brain and the subsequent association and phenotypic activation of microglial cells associated with the amyloid plaque....
15.
Fitch M, Doller C, Combs C, Landreth G, Silver J
J Neurosci
. 1999 Sep;
19(19):8182-98.
PMID: 10493720
Post-traumatic cystic cavitation, in which the size and severity of a CNS injury progress from a small area of direct trauma to a greatly enlarged secondary injury surrounded by glial...
16.
Moeslein F, Myers M, Landreth G
J Biol Chem
. 1999 Sep;
274(38):26697-704.
PMID: 10480872
The protein-tyrosine phosphatase PTP-1B is an important regulator of intracellular protein tyrosine phosphorylation, and is itself regulated by phosphorylation. We report that PTP-1B and its yeast analog, YPTP, are phosphorylated...
17.
Swanson K, Taylor L, Haung L, Burlingame A, Landreth G
J Biol Chem
. 1999 Jan;
274(6):3385-95.
PMID: 9920881
The in vitro phosphorylation of transcription factors by growth factor-activated protein kinases has resulted in the discovery of a number of activities whose identities and relationships to one another are...
18.
Combs C, Johnson D, Cannady S, Lehman T, Landreth G
J Neurosci
. 1999 Jan;
19(3):928-39.
PMID: 9920656
Microglial interaction with amyloid fibrils in the brains of Alzheimer's and prion disease patients results in the inflammatory activation of these cells. We observed that primary microglial cultures and the...
19.
Goodman M, Reigh C, Landreth G
J Neurobiol
. 1998 Sep;
36(4):537-49.
PMID: 9740025
The stress-activated protein kinases (SAPKs) are differentially activated by a variety of cellular stressors in PC12 cells. SAPK activation has been linked to the induction of apoptotic cell death upon...
20.
Swanson K, Reigh C, Landreth G
J Biol Chem
. 1998 Aug;
273(32):19965-71.
PMID: 9685331
Extracellular purine nucleotides elicit a diverse range of biological responses through binding to specific cell surface receptors. The ionotrophic P2X subclass of purinoreceptors respond to ATP by stimulation of calcium...