G C Rice
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Explore the profile of G C Rice including associated specialties, affiliations and a list of published articles.
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48
Citations
1182
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Recent Articles
1.
Guidot D, Bursten S, Rice G, Chaney R, Singer J, Repine A, et al.
Am J Physiol
. 1997 Dec;
273(5):L957-66.
PMID: 9374722
We determined that lisofylline, a potent inhibitor of oleate- and linoleate-containing phosphatidic acid formation (half-maximal inhibitory concentration = 40 nM), prevented oxidant-mediated capillary leak in isolated rat lungs given interleukin-8...
2.
Russell K, Wiens L, Demers G, Galloway D, Le T, Rice G, et al.
Int J Radiat Oncol Biol Phys
. 1996 Dec;
36(5):1099-106.
PMID: 8985032
Purpose: To develop a checkpoint-based strategy for preferential radiosensitization of human tumors with deficient and/or mutant p53. Methods And Materials: A549 human lung adenocarcinoma cell lines differing in their expression...
3.
McMillan J, Weeks R, West J, Bursten S, Rice G, Lovett D
Int J Cancer
. 1996 Aug;
67(4):523-31.
PMID: 8759612
The 92 kDa matrix metalloproteinase (gelatinase B, MMP-9) plays a major role in the facilitation of tumor metastasis and in inflammatory disorders characterized by excessive matrix protein destruction. MMP-9 is...
4.
Clarke E, Rice G, Weeks R, Jenkins N, Nelson R, Bianco J, et al.
Cancer Res
. 1996 Jan;
56(1):105-12.
PMID: 8548748
The effectiveness of endogenous or exogenously administered colony-stimulating factors may be modulated by the presence of hematopoietic inhibitory molecules. Cytotoxic therapy may result in the induction of hematopoietic inhibitors contributing...
5.
Bursten S, Weeks R, West J, Le T, Wilson T, Porubek D, et al.
Circ Shock
. 1994 Sep;
44(1):14-29.
PMID: 7704934
Tumor necrosis factor alpha (TNF alpha), interleukin 1 beta (IL-1 beta), and endotoxin (LPS) are potent pro-inflammatory mediators which induce multiple and diverse biological responses in a wide variety of...
6.
Rice G, Brown P, Nelson R, Bianco J, Singer J, Bursten S
Proc Natl Acad Sci U S A
. 1994 Apr;
91(9):3857-61.
PMID: 8171002
Certain phosphatidic/plasmanic/plasmenic acid (PA) species function as lipid intermediates in cell activation and may function directly as intracellular signaling molecules. PA can also be dephosphorylated to 1,2-diradyl-sn-glycerol by phosphatidate phosphohydrolase....
7.
Rice G, Rosen J, Weeks R, Michnick J, Bursten S, Bianco J, et al.
Shock
. 1994 Apr;
1(4):254-66.
PMID: 7735959
The effect of (R)-1-(5-hydroxyhexyl)-3,7-dimethylxanthine (CT-1501R; the nonproprietary name for CT-1501R approved by the United States Name Council is lisofylline), an inhibitor of second messenger signaling through phosphatidic acid, on release...
8.
Lee J, Horuk R, Rice G, Bennett G, Camerato T, Wood W
J Biol Chem
. 1992 Aug;
267(23):16283-7.
PMID: 1379593
Interleukin 8 (IL-8) and melanocyte growth-stimulatory activity/gro (MGSA) are structurally related proinflammatory cytokines that are chemoattractants and activators of neutrophils. Recently, cDNA clones encoding a high affinity IL-8 receptor (IL-8R-A)...
9.
Rice G, Goeddel D, Cachianes G, Woronicz J, Chen E, Williams S, et al.
Proc Natl Acad Sci U S A
. 1992 Jun;
89(12):5467-71.
PMID: 1376921
We have developed a general method for screening randomly mutagenized expression libraries in mammalian cells by using fluorescence-activated cell sorting (FACS). The cDNA sequence of a secreted protein is randomly...
10.
Lee J, Kuang W, Rice G, Wood W
J Immunol
. 1992 Feb;
148(4):1261-4.
PMID: 1737938
IL-8 is a proinflammatory cytokine that functions as a chemoattractant for neutrophils. Recently, cDNA clones encoding the human neutrophil IL-8R were isolated by an expression cloning strategy. The amino acid...