G C Grosveld
Overview
Explore the profile of G C Grosveld including associated specialties, affiliations and a list of published articles.
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Articles
25
Citations
1992
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0
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Recent Articles
1.
Carella C, Bonten J, Sirma S, Kranenburg T, Terranova S, Klein-Geltink R, et al.
Leukemia
. 2007 May;
21(8):1679-90.
PMID: 17525718
The gene encoding the transcriptional co-activator MN1 is the target of the reciprocal chromosome translocation (12;22)(p13;q12) in some patients with acute myeloid leukemia (AML). In addition, expression array analysis showed...
2.
van Wely K, Meester-Smoor M, Janssen M, Aarnoudse A, Grosveld G, Zwarthoff E
Oncogene
. 2007 Mar;
26(39):5733-40.
PMID: 17369854
The translocation t(12;22)(p13;q11) creates an MN1-TEL fusion gene leading to acute myeloid leukemia. MN1 is a transcription coactivator of the retinoic acid and vitamin D receptors, and TEL (ETV6) is...
3.
Carella C, Bonten J, Rehg J, Grosveld G
Leukemia
. 2006 Jul;
20(9):1582-92.
PMID: 16810199
MN1-TEL is the product of the recurrent t(12;22)(p12;q11) associated with human myeloid malignancies. MN1-TEL functions as an activated transcription factor, exhibiting weak transforming activity in NIH3T3 fibroblasts that depends on...
4.
Kandilci A, Grosveld G
Leukemia
. 2005 Jun;
19(8):1439-45.
PMID: 15931263
Human SET, a target of chromosomal translocation in human leukemia encodes a highly conserved, ubiquitously expressed, nuclear phosphoprotein. SET mediates many functions including chromatin remodeling, transcription, apoptosis and cell cycle...
5.
Zhou S, Schuetz J, Bunting K, Colapietro A, Sampath J, Morris J, et al.
Nat Med
. 2001 Sep;
7(9):1028-34.
PMID: 11533706
Stem cells from bone marrow, skeletal muscle and possibly other tissues can be identified by the 'side-population' (SP) phenotype. Although it has been assumed that expression of ABC transporters is...
6.
Buijs A, Van Rompaey L, Molijn A, Davis J, Vertegaal A, Potter M, et al.
Mol Cell Biol
. 2000 Nov;
20(24):9281-93.
PMID: 11094079
The Tel gene (or ETV6) is the target of the translocation (12;22)(p13;q11) in myeloid leukemia. TEL is a member of the ETS family of transcription factors and contains the pointed...
7.
Potter M, Buijs A, Kreider B, Van Rompaey L, Grosveld G
Blood
. 2000 May;
95(11):3341-8.
PMID: 10828014
The ETS family of proteins is a large group of transcription factors implicated in many aspects of normal hematopoietic development, as well as oncogenesis. For example, the TEL1/ETV6 (TEL1) gene...
8.
Moriggl R, Topham D, Teglund S, Sexl V, Mckay C, Wang D, et al.
Immunity
. 1999 Mar;
10(2):249-59.
PMID: 10072077
Many cytokines activate two highly homologous Stat proteins, 5a and 5b. Mice deficient in both genes lack all growth hormone and prolactin functions but retain functions associated with cytokines such...
9.
Raimondi S, Shurtleff S, Downing J, Rubnitz J, Mathew S, Hancock M, et al.
Blood
. 1997 Dec;
90(11):4559-66.
PMID: 9373267
Although abnormalities involving the short arm of chromosome 12 (12p) are one of the most frequently observed rearrangements in childhood acute lymphoblastic leukemia (ALL), little is known about the frequency...
10.
Boer J, Van Deursen J, Croes H, Fransen J, Grosveld G
Exp Cell Res
. 1997 Apr;
232(1):182-5.
PMID: 9141635
CAN/Nup214, an essential component of the vertebrate nuclear pore complex (NPC), is required for proper cell cycle progression and nucleocytoplasmic transport. It is a member of the FG-repeat-containing family of...