G Aleph Prieto
Overview
Explore the profile of G Aleph Prieto including associated specialties, affiliations and a list of published articles.
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Articles
25
Citations
897
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Recent Articles
1.
Belloso-Iguerategui A, Zamarbide M, Merino-Galan L, Rodriguez-Chinchilla T, Gago B, Santamaria E, et al.
Brain
. 2023 Jul;
146(12):4949-4963.
PMID: 37403195
Learning and memory mainly rely on correct synaptic function in the hippocampus and other brain regions. In Parkinson's disease, subtle cognitive deficits may even precede motor signs early in the...
2.
Lautrup S, Myrup Holst C, Yde A, Asmussen S, Thinggaard V, Larsen K, et al.
Aging Cell
. 2023 Jun;
22(9):e13905.
PMID: 37334527
DNA damage is a central contributor to the aging process. In the brain, a major threat to the DNA is the considerable amount of reactive oxygen species produced, which can...
3.
McQuade A, Kang Y, Hasselmann J, Jairaman A, Sotelo A, Coburn M, et al.
Nat Commun
. 2023 Mar;
14(1):1194.
PMID: 36864071
No abstract available.
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5.
McQuade A, Kang Y, Hasselmann J, Jairaman A, Sotelo A, Coburn M, et al.
Nat Commun
. 2020 Oct;
11(1):5370.
PMID: 33097708
The discovery of TREM2 as a myeloid-specific Alzheimer's disease (AD) risk gene has accelerated research into the role of microglia in AD. While TREM2 mouse models have provided critical insight,...
6.
Forner S, Martini A, Prieto G, Dang C, Rodriguez-Ortiz C, Reyes-Ruiz J, et al.
Sci Rep
. 2019 Nov;
9(1):15936.
PMID: 31685865
Alzheimer's disease (AD), the most common age-related neurodegenerative disorder, is currently conceptualized as a disease of synaptic failure. Synaptic impairments are robust within the AD brain and better correlate with...
7.
Berchtold N, Prieto G, Phelan M, Gillen D, Baldi P, Bennett D, et al.
Neurobiol Aging
. 2019 Mar;
78:142-154.
PMID: 30927700
Exercise has emerged as a powerful variable that can improve cognitive function and delay age-associated cognitive decline and Alzheimer's disease (AD); however, the underlying mechanisms are poorly understood. To determine...
8.
Prieto G, Smith E, Tong L, Nguyen M, Cotman C
ACS Chem Neurosci
. 2019 Jan;
10(3):1197-1203.
PMID: 30695637
In rodent hippocampus, the inflammatory cytokine interleukin-1β (IL-1β) impairs memory and long-term potentiation (LTP), a major form of plasticity that depends on protein synthesis. A better understanding of the mechanisms...
9.
Tong L, Prieto G, Cotman C
J Neuroinflammation
. 2018 May;
15(1):127.
PMID: 29712570
Background: Brain inflammation including increases in inflammatory cytokines such as IL-1β is widely believed to contribute to the pathophysiology of Alzheimer's disease. Although IL-1β-induced impairments in long-term potentiation (LTP) in...
10.
Prieto G, Tong L, Smith E, Cotman C
Neurochem Res
. 2018 Apr;
44(1):49-60.
PMID: 29619614
CNS inflammatory responses are linked to cognitive impairment in humans. Research in animal models supports this connection by showing that inflammatory cytokines suppress long-term potentiation (LTP), the best-known cellular correlate...