Funing Yan
Overview
Explore the profile of Funing Yan including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
70
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Recent Articles
1.
Suarez J, Haapalainen A, Cahill S, Ho M, Yan F, Almo S, et al.
Chem Biol
. 2013 Feb;
20(2):212-22.
PMID: 23438750
Purine nucleoside phosphorylase (PNP) is a target for leukemia, gout, and autoimmune disorders. Dynamic motion of catalytic site loops has been implicated in catalysis, but experimental evidence was lacking. We...
2.
Wang S, Haapalainen A, Yan F, Du Q, Tyler P, Evans G, et al.
Biochemistry
. 2012 Aug;
51(35):6892-4.
PMID: 22891633
Campylobacter and Helicobacter species express a 6-amino-6-deoxyfutalosine N-ribosylhydrolase (HpMTAN) proposed to function in menaquinone synthesis. BuT-DADMe-ImmA is a 36 pM transition state analogue of HpMTAN, and the crystal structure of...
3.
Wang R, Yan F, Qiu D, Jeong J, Jin Q, Kim T, et al.
Bioconjug Chem
. 2012 Mar;
23(4):705-13.
PMID: 22432929
Photoresponsive bioconjugation empowers the development of novel methods for drug discovery, disease diagnosis, and high-throughput screening, among others. In this paper, we report on the characteristics of a traceless photocleavable...
4.
Wang S, Lim J, Thomas K, Yan F, Angeletti R, Schramm V
J Am Chem Soc
. 2012 Jan;
134(3):1468-70.
PMID: 22239413
An enzyme-stabilized nucleophilic water molecule has been implicated at the transition state of Escherichia coli methylthioadenosine nucleosidase (EcMTAN) by transition state analysis and crystallography. We analyzed the EcMTAN mass in...
5.
Yan F, Che F, Nieves E, Weiss L, Angeletti R, Fiser A
Proteomics
. 2011 Aug;
11(20):4109-15.
PMID: 21834138
MS analysis of cross-linked peptides can be used to probe protein contact sites in macromolecular complexes. We have developed a photo-cleavable cross-linker that enhances peptide enrichment, improving the signal-to-noise ratio...
6.
Yan F, Che F, Rykunov D, Nieves E, Fiser A, Weiss L, et al.
Anal Chem
. 2009 Aug;
81(17):7149-59.
PMID: 19642656
Cross-linking analysis of protein complexes and structures by tandem mass spectrometry (MS/MS) has advantages in speed, sensitivity, specificity, and the capability of handling complicated protein assemblies. However, detection and accurate...
7.
Bahns J, Yan F, Qiu D, Wang R, Chen L
Appl Spectrosc
. 2006 Sep;
60(9):989-93.
PMID: 17002823
Stokes and anti-Stokes non-resonant hole-enhanced Raman scattering (HERS) spectra with high signal-to-noise ratio (S/N) are reported for the first time for aqueous phase R6G molecules adsorbed onto random nanoholes in...
8.
Zhang X, Ding J, Song M, Yan F, Yu X
Se Pu
. 2005 Oct;
23(4):436.
PMID: 16250463
No abstract available.
9.
Yan F, Chen L, Tang Q, Wang R
Bioconjug Chem
. 2004 Sep;
15(5):1030-6.
PMID: 15366956
A heterobifunctional photocleavable cross-linker based on an o-nitrobenzyl ester moiety was synthesized. The cross-linker has N-hydroxysuccinimidyl and disulfide groups attached at each end and thus can anchor a protein to...