Fumiko Marttila-Ichihara
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Explore the profile of Fumiko Marttila-Ichihara including associated specialties, affiliations and a list of published articles.
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12
Citations
557
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Recent Articles
1.
Marttila-Ichihara F, Elima K, Auvinen K, Veres T, Rantakari P, Weston C, et al.
FASEB J
. 2017 Mar;
31(6):2477-2491.
PMID: 28251930
In pulmonary fibrosis, an inflammatory reaction and differentiation of myofibroblasts culminate in pathologic deposition of collagen. Amine oxidase copper containing-3 (AOC3) is a cell-surface-expressed oxidase that regulates leukocyte extravasation. Here...
2.
Karikoski M, Marttila-Ichihara F, Elima K, Rantakari P, Hollmen M, Kelkka T, et al.
Clin Cancer Res
. 2014 Oct;
20(24):6452-64.
PMID: 25320356
Purpose: Immunosuppressive leukocytes and vasculature are important host cell components regulating tumor progression. Clever-1/Stabilin-1, a multifunctional scavenger and adhesion receptor, is constitutively present on a subset of type II macrophages...
3.
Metsola J, Maksimow M, Ojaniemi M, Metsola H, Marttila-Ichihara F, Vuolteenaho R, et al.
Pediatr Res
. 2014 Sep;
76(6):515-21.
PMID: 25188742
Background: Adenosine levels are regulated by ecto-5'-nucleotidase/CD73 and adenosine deaminase (ADA). Adenosine regulates endothelial permeability and anti-inflammatory responses via adenosine receptors. Here, the adenosine receptors and purine-converting enzymes were studied...
4.
Aalto K, Autio A, Kiss E, Elima K, Nymalm Y, Veres T, et al.
Blood
. 2011 Aug;
118(13):3725-33.
PMID: 21821708
Leukocyte migration to sites of inflammation is regulated by several endothelial adhesion molecules. Vascular adhesion protein-1 (VAP-1) is unique among the homing-associated molecules as it is both an enzyme that...
5.
Yegutkin G, Marttila-Ichihara F, Karikoski M, Niemela J, Laurila J, Elima K, et al.
Eur J Immunol
. 2011 Apr;
41(5):1231-41.
PMID: 21469131
CD73/ecto-5'-nucleotidase dephosphorylates extracellular AMP into adenosine, and it is a key enzyme in the regulation of adenosinergic signaling. The contribution of host CD73 to tumor growth and anti-tumor immunity has...
6.
Marttila-Ichihara F, Castermans K, Auvinen K, Oude Egbrink M, Jalkanen S, Griffioen A, et al.
J Immunol
. 2010 Feb;
184(6):3164-73.
PMID: 20154208
Vascular adhesion protein-1 (VAP-1) is an endothelial, cell surface-expressed oxidase involved in leukocyte traffic. The adhesive function of VAP-1 can be blocked by anti-VAP-1 Abs and small-molecule inhibitors. However, the...
7.
Marttila-Ichihara F, Auvinen K, Elima K, Jalkanen S, Salmi M
Cancer Res
. 2009 Oct;
69(19):7875-83.
PMID: 19789345
Cancer growth is regulated by several nonmalignant cell types, such as leukocytes and endothelial cells, which reside in the stroma of the tumor. Vascular adhesion protein-1 (VAP-1) is an amine...
8.
Marttila-Ichihara F, Turja R, Miiluniemi M, Karikoski M, Maksimow M, Niemela J, et al.
Blood
. 2008 Apr;
112(1):64-72.
PMID: 18434610
Macrophage mannose receptor (MR) participates in pathogen recognition, clearance of endogenous serum glycoproteins, and antigen presentation. MR is also present on lymphatic vessels, where its function is unknown. Here we...
9.
Marttila-Ichihara F, Smith D, Stolen C, Yegutkin G, Elima K, Mercier N, et al.
Arthritis Rheum
. 2006 Sep;
54(9):2852-62.
PMID: 16947396
Objective: Leukocyte traffic from the blood to the joints is crucial in the pathogenesis of arthritis. A bifunctional endothelial cell-surface glycoprotein, AOC3 (amine oxidase, copper-containing 3; also known as vascular...
10.
Maksimow M, Miiluniemi M, Marttila-Ichihara F, Jalkanen S, Hanninen A
Blood
. 2006 Apr;
108(4):1298-305.
PMID: 16621963
Lymphoma cells are malignant cells of the T- or B-cell lineage that often express many surface markers inappropriately, yet are not recognized as abnormal by the immune system. We modeled...