Frode Vartdal
Overview
Explore the profile of Frode Vartdal including associated specialties, affiliations and a list of published articles.
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Articles
29
Citations
285
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0
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Recent Articles
1.
Polak J, Wagnerberger J, Torsetnes S, Lindeman I, Hoglund R, Vartdal F, et al.
Front Cell Neurosci
. 2023 Jun;
17:1189709.
PMID: 37362001
The phenotypes of B lineage cells that produce oligoclonal IgG in multiple sclerosis have not been unequivocally determined. Here, we utilized single-cell RNA-seq data of intrathecal B lineage cells in...
2.
Lindeman I, Polak J, Qiao S, Holmoy T, Hoglund R, Vartdal F, et al.
Eur J Immunol
. 2022 Jan;
52(4):550-565.
PMID: 35094395
Clonally related B cells infiltrate the brain, meninges, and cerebrospinal fluid of MS patients, but the mechanisms driving the B-cell response and shaping the immunoglobulin repertoires remain unclear. Here, we...
3.
Sollid L, Lundin K, Leivestad T, Spurkland A, Vartdal F
Immunogenetics
. 2021 May;
73(3):203-205.
PMID: 33956175
No abstract available.
4.
Tomescu-Baciu A, Johansen J, Holmoy T, Greiff V, Stensland M, Antonio de Souza G, et al.
J Neuroimmunol
. 2019 Jun;
333:576966.
PMID: 31153015
In multiple sclerosis (MS), B cells are trafficking across the blood-brain barrier, but it is not known how this relates to the synthesis of oligoclonal IgG. We used quantitative mass...
5.
Tomescu-Baciu A, Vartdal F, Holmoy T, Vedeler C, Lossius A
Ann Clin Transl Neurol
. 2018 Oct;
5(10):1303-1309.
PMID: 30349866
We have previously shown that plasmablasts of the G1m1 allotype of IgG1 are selectively enriched in the cerebrospinal fluid of G1m1/G1m3 heterozygous patients with multiple sclerosis, whereas both allotypes are...
6.
Hoglund R, Polak J, Vartdal F, Holmoy T, Lossius A
Mult Scler Relat Disord
. 2018 Sep;
26:90-95.
PMID: 30243235
Background: B cells may contribute to the immunopathogenesis of multiple sclerosis (MS). Dimethyl fumarate (DMF) has recently been shown to reduce the frequency of memory B cells in blood, but...
7.
Lossius A, Tomescu-Baciu A, Holmoy T, Vedeler C, Rosjo E, Lorentzen A, et al.
Ann Clin Transl Neurol
. 2017 Oct;
4(10):756-761.
PMID: 29046884
Immunoglobulin gamma (IgG) heavy chain genes are associated with susceptibility to multiple sclerosis (MS) and IgG levels in the cerebrospinal fluid (CSF). However, how these variants are implicated in disease...
8.
Lossius A, Johansen J, Vartdal F, Holmoy T
Ann Clin Transl Neurol
. 2016 Apr;
3(4):295-306.
PMID: 27081660
T cells and B cells are crucial in the initiation and maintenance of multiple sclerosis (MS), and the activation of these cells is believed to be mediated through specific recognition...
9.
Johansen J, Vartdal F, Desmarais C, Tutturen A, de Souza G, Lossius A, et al.
Clin Immunol
. 2015 Jun;
160(2):211-25.
PMID: 26055752
The mechanisms driving the intrathecal synthesis of IgG in multiple sclerosis (MS) are unknown. We combined high-throughput sequencing of transcribed immunoglobulin heavy-chain variable (IGHV) genes and mass spectrometry to chart...
10.
Lossius A, Johansen J, Vartdal F, Robins H, Jurate Saltyte B, Holmoy T, et al.
Eur J Immunol
. 2014 Aug;
44(11):3439-52.
PMID: 25103993
Epstein-Barr virus (EBV) has long been suggested as a pathogen in multiple sclerosis (MS). Here, we used high-throughput sequencing to determine the diversity, compartmentalization, persistence, and EBV-reactivity of the T-cell...