Friedrich Grimminger
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Explore the profile of Friedrich Grimminger including associated specialties, affiliations and a list of published articles.
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318
Citations
11575
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Recent Articles
11.
Henneke I, Pilz C, Wilhelm J, Alexopoulos I, Ezaddoustdar A, Mukhametshina R, et al.
Am J Physiol Cell Physiol
. 2024 Apr;
326(6):C1637-C1647.
PMID: 38646782
Bleomycin (BLM)-induced lung injury in mice is a valuable model for investigating the molecular mechanisms that drive inflammation and fibrosis and for evaluating potential therapeutic approaches to treat the disease....
12.
Yogeswaran A, Gall H, Funderich M, Wilkins M, Howard L, Kiely D, et al.
Chest
. 2024 Mar;
166(3):585-603.
PMID: 38508334
Background: Pulmonary hypertension (PH) is a heterogeneous disease with a poor prognosis. Accurate risk stratification is essential for guiding treatment decisions in pulmonary arterial hypertension (PAH). Although various risk models...
13.
Turkowski K, Herzberg F, Gunther S, Weigert A, Haselbauer T, Fink L, et al.
Oncogene
. 2024 Feb;
43(16):1178-1189.
PMID: 38396293
Dual-specificity phosphatase 8 (DUSP8) plays an important role as a selective c-Jun N-terminal kinase (JNK) phosphatase in mitogen-activated protein kinase (MAPK) signaling. In this study, we found that DUSP8 is...
14.
Hadzic S, Wu C, Gredic M, Pak O, Loku E, Kraut S, et al.
Eur Respir J
. 2023 Oct;
62(5).
PMID: 37884305
Background: COPD is an incurable disease and a leading cause of death worldwide. In mice, fibroblast growth factor (FGF)10 is essential for lung morphogenesis, and in humans, polymorphisms in the...
15.
Ley L, Grimminger F, Richter M, Tello K, Ghofrani A, Bandorski D
Dtsch Arztebl Int
. 2023 Oct;
120(48):823-830.
PMID: 37882345
Background: Up to 1% of the world population and 10% of all persons over age 65 suffer from pulmonary hypertension (PH). The latency from the first symptom to the diagnosis...
16.
Cekay M, Arndt P, Dumitrascu R, Savai R, Braeuninger A, Gattenloehner S, et al.
Front Oncol
. 2023 Sep;
13:1182391.
PMID: 37655099
Up to 20% of all non-small cell lung cancer patients harbor tumor specific driver mutations that are effectively treated with tyrosine kinase inhibitors. However, for the rare EGFR deletion-insertion mutation...
17.
Yogeswaran A, Zedler D, Richter M, Steinke S, Rako Z, Kremer N, et al.
Front Med (Lausanne)
. 2023 Aug;
10:1207474.
PMID: 37547612
Background: Cardiac interactions with organs such as the liver or kidneys have been described in different cardiovascular diseases. However, the clinical relevance of hepatorenal dysfunction in chronic thromboembolic pulmonary hypertension...
18.
Karger A, Mansouri S, Leisegang M, Weigert A, Gunther S, Kuenne C, et al.
EMBO J
. 2023 Aug;
42(18):e111620.
PMID: 37545364
Long noncoding RNAs (lncRNAs) influence the transcription of gene networks in many cell types, but their role in tumor-associated macrophages (TAMs) is still largely unknown. We found that the lncRNA...
19.
Yogeswaran A, Richter M, Husain-Syed F, Rako Z, Sommer N, Grimminger F, et al.
Front Cardiovasc Med
. 2023 May;
10:1161041.
PMID: 37234373
Background: Volume overload is often associated with clinical deterioration in precapillary pulmonary hypertension (PH). However, thorough assessment of volume overload is complex and therefore not routinely performed. We examined whether...
20.
Wu C, Cilic A, Pak O, Dartsch R, Wilhelm J, Wujak M, et al.
Am J Respir Crit Care Med
. 2023 May;
207(12):1576-1590.
PMID: 37219322
Tobacco smoking and air pollution are primary causes of chronic obstructive pulmonary disease (COPD). However, only a minority of smokers develop COPD. The mechanisms underlying the defense against nitrosative/oxidative stress...