Friedrich Becker
Overview
Explore the profile of Friedrich Becker including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
137
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0
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Recent Articles
1.
Hupa-Breier K, Schenk H, Campos-Murguia A, Wellhoner F, Heidrich B, Dywicki J, et al.
Mol Metab
. 2025 Jan;
93:102104.
PMID: 39855563
Objective: Metabolic dysfunction-associated steatotic liver disease (MASLD) is the most common cause of chronic liver disease, especially in patients with severe obesity. However, current mouse models for MASLD do not...
2.
Mapfumo P, Solomun J, Becker F, Moek E, Leiske M, Rudolph L, et al.
Macromol Biosci
. 2024 Mar;
24(7):e2400002.
PMID: 38484731
Polymeric nanoparticles (NPs) with an integrated dual delivery system enable the controlled release of bioactive molecules and drugs, providing therapeutic advantages. Key design targets include high biocompatibility, cellular uptake, and...
3.
Becker F, Behrends M, Rudolph K
Redox Biol
. 2023 May;
63:102725.
PMID: 37257276
Dietary restriction (DR) is the most powerful intervention to enhance health and lifespan across species. However, recent findings indicate that DR started in late life has limited capacity to induce...
4.
Solomun J, Martin L, Mapfumo P, Moek E, Amro E, Becker F, et al.
J Nanobiotechnology
. 2022 Jul;
20(1):336.
PMID: 35842657
Cationic non-viral vectors show great potential to introduce genetic material into cells, due to their ability to transport large amounts of genetic material and their high synthetic versatility. However, designing...
5.
6.
Scheffold A, Baig A, Chen Z, von Lohneysen S, Becker F, Morita Y, et al.
Leukemia
. 2019 Nov;
34(4):1125-1134.
PMID: 31728056
Accumulation of DNA damage and myeloid-skewed differentiation characterize aging of the hematopoietic system, yet underlying mechanisms remain incompletely understood. Here, we show that aging hematopoietic progenitor cells particularly of the...
7.
Schworer S, Becker F, Feller C, Baig A, Kober U, Henze H, et al.
Nature
. 2019 Aug;
572(7769):E11-E15.
PMID: 31363230
An Amendment to this paper has been published and can be accessed via a link at the top of the paper.
8.
Chen Z, Amro E, Becker F, Holzer M, Rasa S, Njeru S, et al.
J Exp Med
. 2018 Dec;
216(1):152-175.
PMID: 30530755
Organism aging is characterized by increased inflammation and decreased stem cell function, yet the relationship between these factors remains incompletely understood. This study shows that aged hematopoietic stem and progenitor...
9.
Schworer S, Becker F, Feller C, Baig A, Kober U, Henze H, et al.
Nature
. 2016 Dec;
540(7633):428-432.
PMID: 27919074
The functionality of stem cells declines during ageing, and this decline contributes to ageing-associated impairments in tissue regeneration and function. Alterations in developmental pathways have been associated with declines in...
10.
Avila A, Illing A, Becker F, Maerz L, Morita Y, Philipp M, et al.
Nucleic Acids Res
. 2016 May;
44(13):6252-61.
PMID: 27137888
Reduced capacity of genome maintenance represents a problem for any organism, potentially causing premature death, carcinogenesis, or accelerated ageing. Strikingly though, loss of certain genome stability factors can be beneficial,...