Friederike Leesch
Overview
Explore the profile of Friederike Leesch including associated specialties, affiliations and a list of published articles.
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5
Citations
73
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Recent Articles
1.
Shah A, Leesch F, Lorenzo-Orts L, Grundmann L, Novatchkova M, Haselbach D, et al.
bioRxiv
. 2024 Sep;
PMID: 39257781
Protein synthesis during vertebrate embryogenesis is driven by ribosomes of two distinct origins: maternal ribosomes synthesized during oogenesis and stored in the egg, and somatic ribosomes, produced by the developing...
2.
Lorenzo-Orts L, Strobl M, Steinmetz B, Leesch F, Pribitzer C, Roehsner J, et al.
EMBO Rep
. 2024 Jan;
25(1):404-427.
PMID: 38177902
Maternal mRNAs are essential for protein synthesis during oogenesis and early embryogenesis. To adapt translation to specific needs during development, maternal mRNAs are translationally repressed by shortening the polyA tails....
3.
Leesch F, Lorenzo-Orts L, Pribitzer C, Grishkovskaya I, Roehsner J, Chugunova A, et al.
Nature
. 2023 Jan;
613(7945):712-720.
PMID: 36653451
Ribosomes are produced in large quantities during oogenesis and are stored in the egg. However, the egg and early embryo are translationally repressed. Here, using mass spectrometry and cryo-electron microscopy...
4.
Huth M, Santini L, Galimberti E, Ramesmayer J, Titz-Teixeira F, Sehlke R, et al.
Genes Dev
. 2022 Mar;
36(5-6):348-367.
PMID: 35241478
Cell fate transitions depend on balanced rewiring of transcription and translation programs to mediate ordered developmental progression. Components of the nonsense-mediated mRNA decay (NMD) pathway have been implicated in regulating...
5.
Nagosa S, Leesch F, Putin D, Bhattacharya S, Altshuler A, Serror L, et al.
Stem Cell Reports
. 2017 Dec;
9(6):1991-2004.
PMID: 29198823
miR-184 is a highly evolutionary conserved microRNA (miRNA) from fly to human. The importance of miR-184 was underscored by the discovery that point mutations in miR-184 gene led to corneal/lens...