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Freek G Bouwman

Explore the profile of Freek G Bouwman including associated specialties, affiliations and a list of published articles. Areas
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Articles 76
Citations 1001
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Recent Articles
1.
Bouwens B, Magdeleyns E, Thomassen M, Bouwman F, Suylen D, Hackeng T, et al.
J Thromb Haemost . 2024 Nov; 23(2):641-650. PMID: 39613106
Background: Neutrophils are known to externalize their DNA and intracellular contents to neutralize invading pathogens. This process may enhance blood coagulation during inflammation. Tissue factor (TF) pathway inhibitor (TFPI) binds...
2.
Bahram Sangani N, Koetsier J, Gomes A, Diogo M, Fernandes T, Bouwman F, et al.
Cell Mol Life Sci . 2024 Sep; 81(1):410. PMID: 39305343
Rett syndrome (RTT) is a neurodevelopmental disorder caused by de novo mutations in the MECP2 gene. Although miRNAs in extracellular vesicles (EVs) have been suggested to play an essential role...
3.
Cuijpers I, Dohmen C, Bouwman F, Troost F, Sthijns M
Front Nutr . 2024 Sep; 11:1377071. PMID: 39285862
Introduction: Skeletal muscle regeneration is impaired in elderly. An oxidative stress-induced decrease in differentiation capacity of muscle satellite cells is a key factor in this process. The aim of this...
4.
Beaumont J, Barbeau L, Ju J, Savelkouls K, Bouwman F, Zonneveld M, et al.
J Extracell Vesicles . 2024 Jul; 13(7):e12449. PMID: 39001708
Hypoxia is a common feature of solid tumours and activates adaptation mechanisms in cancer cells that induce therapy resistance and has profound effects on cellular metabolism. As such, hypoxia is...
5.
Groven R, Kuik C, Greven J, Mert U, Bouwman F, Poeze M, et al.
Bone Joint Res . 2024 May; 13(5):214-225. PMID: 38699779
Aims: The aim of this study was to determine the fracture haematoma (fxH) proteome after multiple trauma using label-free proteomics, comparing two different fracture treatment strategies. Methods: A porcine multiple...
6.
Beaumont J, Ju J, Barbeau L, Demers I, Savelkouls K, Derks K, et al.
Radiother Oncol . 2023 Oct; 190:109968. PMID: 37898438
Background And Purpose: Hypoxia is a common feature of tumours, associated with poor prognosis due to increased resistance to radio- and chemotherapy and enhanced metastasis development. Previously we demonstrated that...
7.
Canfora E, Vliex L, Wang T, Nauta A, Bouwman F, Holst J, et al.
Front Nutr . 2023 Aug; 10:1200645. PMID: 37529001
Background: Infusion of short-chain fatty acids (SCFA) to the distal colon beneficially affects human substrate and energy metabolism. Here, we hypothesized that the combination of 2'-fucosyllactose (2'-FL) with resistant starch...
8.
Thomassen M, Bouwens B, Wichapong K, Suylen D, Bouwman F, Hackeng T, et al.
J Thromb Haemost . 2023 Jan; 21(5):1214-1226. PMID: 36716968
Background: Tissue factor pathway inhibitor (TFPI) is an important regulator of coagulation and a link between inflammation and thrombosis. During thrombotic events, TFPI is proteolytically inactivated by neutrophil elastase while...
9.
van Deuren T, Smolders L, Hartog A, Bouwman F, Holst J, Venema K, et al.
Front Nutr . 2023 Jan; 9:1066950. PMID: 36687671
Background: Short chain fatty acids (SCFA) are increasingly recognized for their potential ability to alleviate obesity-associated chronic low-grade inflammation and disturbed energy homeostasis. Evidence suggests that an increase in circulating...
10.
Qiao Q, Bouwman F, van Baak M, Roumans N, Vink R, Mariman E
J Clin Endocrinol Metab . 2022 Apr; 107(7):1920-1929. PMID: 35366329
Context: Long-term weight loss (WL) maintenance is the biggest challenge for overweight and obesity because of the almost unavoidable phenomenon of partial or even total weight regain (WR) after WL....