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Fredrik Soderbom

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Articles 31
Citations 444
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Recent Articles
21.
Larsson P, Hinas A, Ardell D, Kirsebom L, Virtanen A, Soderbom F
Genome Res . 2008 Mar; 18(6):888-99. PMID: 18347326
Genome data are increasingly important in the computational identification of novel regulatory non-coding RNAs (ncRNAs). However, most ncRNA gene-finders are either specialized to well-characterized ncRNA gene families or require comparisons...
22.
Hinas A, Reimegard J, Wagner E, Nellen W, Ambros V, Soderbom F
Nucleic Acids Res . 2007 Oct; 35(20):6714-26. PMID: 17916577
Small RNAs play crucial roles in regulation of gene expression in many eukaryotes. Here, we report the cloning and characterization of 18-26 nt RNAs in the social amoeba Dictyostelium discoideum....
23.
Sandrini M, Soderbom F, Mikkelsen N, Piskur J
J Mol Biol . 2007 Apr; 369(3):653-64. PMID: 17448496
The salvage of deoxyribonucleosides in the social amoeba Dictyostelium discoideum, which has an extremely A+T-rich genome, was investigated. All native deoxyribonucleosides were phosphorylated by D. discoideum cell extracts and we...
24.
Hinas A, Soderbom F
Curr Genet . 2006 Dec; 51(3):141-59. PMID: 17171561
The traditional view of RNA being merely an intermediate in the transfer of genetic information, as mRNA, spliceosomal RNA, tRNA, and rRNA, has become outdated. The recent discovery of numerous...
25.
Kyriakopoulou C, Larsson P, Liu L, Schuster J, Soderbom F, Kirsebom L, et al.
RNA . 2006 Jul; 12(9):1603-11. PMID: 16829670
We have detected a surprising heterogeneity among human spliceosomal U1 small nuclear RNA (snRNA). Most interestingly, we have identified three U1 snRNA variants that lack complementarity to the canonical 5'...
26.
Hinas A, Larsson P, Avesson L, Kirsebom L, Virtanen A, Soderbom F
Eukaryot Cell . 2006 Jun; 5(6):924-34. PMID: 16757740
Most eukaryotic mRNAs depend upon precise removal of introns by the spliceosome, a complex of RNAs and proteins. Splicing of pre-mRNA is known to take place in Dictyostelium discoideum, and...
27.
Popova B, Kuhlmann M, Hinas A, Soderbom F, Nellen W
Nucleic Acids Res . 2006 Feb; 34(3):773-84. PMID: 16456031
We have identified a putative RNA helicase from Dictyostelium that is closely related to drh-1, the 'dicer-related-helicase' from Caenorhabditis elegans and that also has significant similarity to proteins from vertebrates...
28.
Kuhlmann M, Borisova B, Kaller M, Larsson P, Stach D, Na J, et al.
Nucleic Acids Res . 2005 Nov; 33(19):6405-17. PMID: 16282589
We have identified a DNA methyltransferase of the Dnmt2 family in Dictyostelium that was denominated DnmA. Expression of the dnmA gene is downregulated during the developmental cycle. Overall DNA methylation...
29.
Soderbom F, Svard S, Kirsebom L
J Mol Biol . 2005 Aug; 352(1):22-7. PMID: 16081101
In this study, we have used various tRNA(Tyr)Su3 precursor (pSu3) derivatives that are processed less efficiently by RNase P to investigate if the 5' leader is a target for RNase...
30.
Aspegren A, Hinas A, Larsson P, Larsson A, Soderbom F
Nucleic Acids Res . 2004 Aug; 32(15):4646-56. PMID: 15333696
The quest for non-coding RNAs (ncRNAs) in the last few years has revealed a surprisingly large number of small RNAs belonging to previously known as well as entirely novel classes....