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Frederique Van de Velde

Explore the profile of Frederique Van de Velde including associated specialties, affiliations and a list of published articles. Areas
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Articles 15
Citations 196
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Recent Articles
1.
Puengel T, Lefere S, Hundertmark J, Kohlhepp M, Penners C, Van de Velde F, et al.
Int J Mol Sci . 2022 Jun; 23(12). PMID: 35743140
(1) Background: With new potential drug targets emerging, combination therapies appear attractive to treat non-alcoholic steatohepatitis (NASH) and fibrosis. Chemokine receptor CCR2/5 antagonists can improve fibrosis by reducing monocyte infiltration...
2.
Van de Velde F, Ouwens D, Batens A, van Nieuwenhove Y, Lapauw B
Cytokine . 2021 May; 144:155587. PMID: 34052657
Aim: Dysfunction of adipose and muscle tissue associates with obesity-related co-morbidities such as insulin resistance (IR) and inflammation. This study investigates changes in systemic and tissue-specific markers of IR and...
3.
Decock A, Verroken C, Van de Velde F, Vilsboll T, Holst J, TSjoen G, et al.
Clin Endocrinol (Oxf) . 2021 Mar; 95(1):65-73. PMID: 33715210
Objective: Acromegaly is accompanied by abnormalities in glucose and lipid metabolism which improve upon treatment. Few studies have investigated whether these improvements differ between treatment modalities. This study aimed to...
4.
Van de Velde F, Deventer K, Van Gansbeke W, Van Eenoo P, Van Renterghem P, Fiers T, et al.
J Steroid Biochem Mol Biol . 2021 Feb; 209:105851. PMID: 33610798
Objective: Men with obesity often have low total and, with increasing adiposity, also low free testosterone (T) levels, which can partially restore during weight loss. Although this is partly explained...
5.
Van de Velde F, Lapauw B
Nat Rev Endocrinol . 2021 Feb; 17(5):317. PMID: 33536609
No abstract available.
6.
Fahlbusch P, Knebel B, Horbelt T, Barbosa D, Nikolic A, Jacob S, et al.
Int J Mol Sci . 2020 Jun; 21(11). PMID: 32532003
Fatty liver occurs from simple steatosis with accumulated hepatic lipids and hepatic insulin resistance to severe steatohepatitis, with aggravated lipid accumulation and systemic insulin resistance, but this progression is still...
7.
Van de Velde F, Reyns T, Toye K, Fiers T, Kaufman J, TSjoen G, et al.
Clin Endocrinol (Oxf) . 2019 Dec; 92(3):214-221. PMID: 31821582
Objective: Guidelines recommend using fasting samples to evaluate testosterone (T) levels in men, as free and total T levels decrease postprandially. However, it is not clear whether these dynamics are...
8.
Van de Velde F, Bekaert M, Geerts A, Hoorens A, Batens A, Shadid S, et al.
Endocr Connect . 2019 Aug; 8(9):1294-1301. PMID: 31470414
Purpose: Obese subjects with nonalcoholic fatty liver disease (NAFLD) are more prone to develop additional metabolic disturbances such as systemic insulin resistance (IR) and type 2 diabetes. NAFLD is defined...
9.
Horbelt T, Knebel B, Fahlbusch P, Barbosa D, Herzfeld de Wiza D, Van de Velde F, et al.
Biochim Biophys Acta Mol Basis Dis . 2019 Jul; 1865(10):2671-2684. PMID: 31336149
Secreted frizzled-related protein (sFRP) 4 is an adipokine with increased expression in white adipose tissue from obese subjects with type 2 diabetes and non-alcoholic fatty liver disease (NAFLD). Yet, it...
10.
Van de Velde F, Bekaert M, Hoorens A, Geerts A, TSjoen G, Fiers T, et al.
Asian J Androl . 2019 Jul; 22(3):252-257. PMID: 31274482
Men with obesity often present with low testosterone (T) and sex hormone-binding globulin (SHBG) levels. Several mechanisms for this have been proposed, but as SHBG is secreted by hepatocytes and...