Frederik Roels
Overview
Explore the profile of Frederik Roels including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
15
Citations
1480
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
11.
Fabian J, Lodrini M, Oehme I, Schier M, Thole T, Hielscher T, et al.
Cancer Res
. 2014 Jan;
74(9):2604-16.
PMID: 24419085
Neuroblastoma is an embryonic solid tumor of neural crest origin and accounts for 11% of all cancer-related deaths in children. Novel therapeutic strategies are therefore urgently required. MYCN oncogene amplification,...
12.
Brockmann M, Poon E, Berry T, Carstensen A, Deubzer H, Rycak L, et al.
Cancer Cell
. 2013 Jun;
24(1):75-89.
PMID: 23792191
Amplification of MYCN is a driver mutation in a subset of human neuroendocrine tumors, including neuroblastoma. No small molecules that target N-Myc, the protein encoded by MYCN, are clinically available....
13.
Decarolis B, Schneider C, Hero B, Simon T, Volland R, Roels F, et al.
J Clin Oncol
. 2013 Jan;
31(7):944-51.
PMID: 23341514
Purpose: Radioiodinated metaiodobenzylguanidine ((123)I-mIBG) scintigraphy is an established imaging method in neuroblastoma. Semiquantitative scoring systems have been developed to assess the extent of disease and response to chemotherapy. We present...
14.
Hopker K, Hagmann H, Khurshid S, Chen S, Hasskamp P, Seeger-Nukpezah T, et al.
EMBO J
. 2012 Aug;
31(20):3961-75.
PMID: 22909821
Following genotoxic stress, cells activate a complex signalling network to arrest the cell cycle and initiate DNA repair or apoptosis. The tumour suppressor p53 lies at the heart of this...
15.
Bruns I, Cadeddu R, Brueckmann I, Frobel J, Geyh S, Bust S, et al.
Blood
. 2012 Apr;
120(13):2620-30.
PMID: 22517906
Multiple myeloma (MM) is a clonal plasma cell disorder frequently accompanied by hematopoietic impairment. We show that hematopoietic stem and progenitor cells (HSPCs), in particular megakaryocyte-erythrocyte progenitors, are diminished in...