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Jessica Theissen

Explore the profile of Jessica Theissen including associated specialties, affiliations and a list of published articles. Areas
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Articles 22
Citations 1471
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Recent Articles
1.
Rosswog C, Fassunke J, Ernst A, Schomig-Markiefka B, Merkelbach-Bruse S, Bartenhagen C, et al.
Br J Cancer . 2023 Feb; 128(8):1559-1571. PMID: 36807339
Background: Genomic alterations of the anaplastic lymphoma kinase gene (ALK) occur recurrently in neuroblastoma, a pediatric malignancy of the sympathetic nervous system. However, information on their development over time has...
2.
Szymansky A, Kruetzfeldt L, Heukamp L, Hertwig F, Theissen J, Deubzer H, et al.
J Pers Med . 2021 Aug; 11(8). PMID: 34442335
For many years, the risk-based therapy stratification of children with neuroblastoma has relied on clinical and molecular covariates. In recent years, genome analysis has revealed further alterations defining risk, tumor...
3.
Koche R, Rodriguez-Fos E, Helmsauer K, Burkert M, MacArthur I, Maag J, et al.
Nat Genet . 2020 Feb; 52(4):464. PMID: 32107479
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
4.
Koche R, Rodriguez-Fos E, Helmsauer K, Burkert M, MacArthur I, Maag J, et al.
Nat Genet . 2019 Dec; 52(1):29-34. PMID: 31844324
Extrachromosomal circularization of DNA is an important genomic feature in cancer. However, the structure, composition and genome-wide frequency of extrachromosomal circular DNA have not yet been profiled extensively. Here, we...
5.
Ackermann S, Cartolano M, Hero B, Welte A, Kahlert Y, Roderwieser A, et al.
Science . 2018 Dec; 362(6419):1165-1170. PMID: 30523111
Neuroblastoma is a pediatric tumor of the sympathetic nervous system. Its clinical course ranges from spontaneous tumor regression to fatal progression. To investigate the molecular features of the divergent tumor...
6.
Depuydt P, Boeva V, Hocking T, Cannoodt R, Ambros I, Ambros P, et al.
J Natl Cancer Inst . 2018 Mar; 110(10):1084-1093. PMID: 29514301
Background: Neuroblastoma is characterized by substantial clinical heterogeneity. Despite intensive treatment, the survival rates of high-risk neuroblastoma patients are still disappointingly low. Somatic chromosomal copy number aberrations have been shown...
7.
Hero B, Clement N, Ora I, Pierron G, Lapouble E, Theissen J, et al.
J Pediatr Hematol Oncol . 2017 Nov; 40(2):93-98. PMID: 29135842
Opsoclonus myoclonus syndrome (OMS), often called "dancing eyed syndrome," is a rare neurological condition associated with neuroblastoma in the majority of all childhood cases. Genomic copy number profiles have shown...
8.
Powers J, Tsanov K, Pearson D, Roels F, Spina C, Ebright R, et al.
Nature . 2016 Jul; 535(7611):246-51. PMID: 27383785
Poor prognosis in neuroblastoma is associated with genetic amplification of MYCN. MYCN is itself a target of let-7, a tumour suppressor family of microRNAs implicated in numerous cancers. LIN28B, an...
9.
Peifer M, Hertwig F, Roels F, Dreidax D, Gartlgruber M, Menon R, et al.
Nature . 2015 Oct; 526(7575):700-4. PMID: 26466568
Neuroblastoma is a malignant paediatric tumour of the sympathetic nervous system. Roughly half of these tumours regress spontaneously or are cured by limited therapy. By contrast, high-risk neuroblastomas have an...
10.
Schramm A, Koster J, Assenov Y, Althoff K, Peifer M, Mahlow E, et al.
Nat Genet . 2015 Jun; 47(8):872-7. PMID: 26121086
Neuroblastoma is a malignancy of the developing sympathetic nervous system that is often lethal when relapse occurs. We here used whole-exome sequencing, mRNA expression profiling, array CGH and DNA methylation...